BCR-ABL, Sepsis Added

January 5, 2011

Descriptions covering the following test and condition were recently added to Lab Tests Online:

BCR-ABL: The test for the BCR-ABL gene sequence is used (a) to help diagnose chronic myelogenous leukemia (CML) and a type of acute lymphocytic leukemia (ALL) in which the BCR-ABL gene sequence is present (BCR-ABL positive), (b) to monitor response to treatment, and (c) to monitor for disease recurrence. The BCR-ABL gene sequence is an acquired abnormality found in chromosome 22. The presence of the BCR-ABL gene sequence confirms the clinical diagnosis of CML and BCR-ABL-positive ALL.

Sepsis: Sepsis is the name given to a systemic inflammatory response caused by a bacterial infection. The infection may begin in one site of the body and then spread to the blood (bacteremia) and possibly to other sites. Sepsis is a serious condition that can progress from sepsis to severe sepsis and then to septic shock with the failure of one or more organs. Testing is ordered to help diagnose sepsis, distinguish it from other conditions, and to evaluate and monitor the function of the affected person's organs, blood oxygenation, and acid-base balance.