Antiphospholipid Syndrome Added to the Site

March 22, 2011

March 22, 2011--A new article covering the condition Antiphospholipid Syndrome was recently added to Lab Tests Online.

Antiphospholipid syndrome, also known as APS or Hughes syndrome, is an autoimmune disorder and a hypercoagulable disorder. It is associated with the production of one or more antiphospholipid antibodies, which interfere with the blood clotting process.

The primary antiphospholipid antibodies seen with APS include lupus anticoagulant, cardiolipin antibody, and beta-2 glycoprotein I (β2GP1) antibody. These antibodies increase an affected person's risk of developing recurrent inappropriate blood clots in both veins and arteries. Laboratory tests to detect these autoantibodies are used to help diagnose APS and to distinguish it from other causes of symptoms and complications.

APS may affect anyone but is most frequently seen in women of child-bearing age and in those with another autoimmune disorder. It is associated with thrombotic episodes, thrombocytopenia, and with pregnancy complications such as preeclampsia and recurrent miscarriages.