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Chlamydia


Formal name: Chlamydia trachomatis culture; Chlamydia trachomatis DNA Probe; Chlamydia trachomatis by Amplified Detection; Chlamydia trachomatis by Direct Antigen Detection (DFA)
Related tests: Gonorrhea

The Test Sample

What is being tested?

The test is looking for evidence of infection by the bacterium Chlamydia trachomatis. Chlamydia is the most common bacterial sexually transmitted disease (STD) in the United States and is especially common among people 15 to 25 years of age. It is estimated that 3 million Americans are infected with chlamydia each year, although this number may be higher. Since many people do not experience any symptoms, cases often go undiagnosed and unreported; still, over 1 million new cases are reported each year. Diagnosing and treating chlamydia is very important to prevent long-term complications and spread of the infection to others.

Chlamydia is generally transmitted through sexual contact (oral, vaginal, or anal) with an infected partner. Risk factors include having multiple sex partners, coinfection or previous infection with another STD, and not using barrier contraception consistently. An infected mother can spread the disease to her baby during childbirth. These babies are in danger of developing conjunctivitis, an inflammation that can threaten eyesight, and pneumonia.

About 75% of infected women and 50% of infected men have no symptoms; some may experience only mild symptoms. For women, symptoms, if they occur, include bleeding between menstrual periods and after sexual intercourse, abdominal pain, painful intercourse, and an abnormal vaginal discharge. For men, symptoms include pus or milky discharge from the penis and inflammation of the prostate (prostatitis) or of the rectal area (proctitis). Both sexes can experience painful or frequent urination.

Chlamydia is easily treated with a course of antibiotics, but if left untreated, it can cause severe reproductive and other health problems. If left untreated, 40% of women may develop pelvic inflammatory disease (PID) from infections that start on the cervix but that can spread to the fallopian tubes and ovaries. This can cause infertility and increase the risk of tubal (ectopic) pregnancy, which is often fatal. Women who are infected and pregnant may experience heavy bleeding before delivery and premature rupture of the membranes. Men, too, may become sterile. Both sexes may develop rectal itching and red, swollen, itchy eyes.

How is the sample collected for testing?

Generally, your doctor will use a swab or brush to take a cell sample or secretion from the infected area, such as the cervix, urethra, penis, anus, or throat. Urine specimens are acceptable if the particular lab where the sample is sent uses a molecular method that is validated for this sample.

NOTE: If undergoing medical tests makes you or someone you care for anxious, embarrassed, or even difficult to manage, you might consider reading one or more of the following articles: Coping with Test Pain, Discomfort, and Anxiety, Tips on Blood Testing, Tips to Help Children through Their Medical Tests, and Tips to Help the Elderly through Their Medical Tests.

Another article, Follow That Sample, provides a glimpse at the collection and processing of a blood sample and throat culture.

Is any test preparation needed to ensure the quality of the sample?

No test preparation is needed.