Diabetes-related Autoantibodies
Article Sources
NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.
Hussain, A. and Vincent, M. (Updated 2009 July 2). Diabetes Mellitus, Type 1. eMedicine On-line information]. Available online at http://emedicine.medscape.com/article/117739-overview through http://emedicine.medscape.com. Accessed January 2010.
Titus, K. (2009 August). Diabetes markers—closer than you think? CAP Today [On-line information]. Available online through http://www.cap.org. Accessed January 2010.
(2008 May). Overview of Diabetes in Children and Adolescents. National Diabetes Education Information [On-line information]. Available online at http://ndep.nih.gov/media/diabetes/youth/youth_FS.htm through http://ndep.nih.gov. Accessed January 2010.
S4 Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 355-356.
Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 292-293.
Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 620-621, 630-631.
Kronenberg, H. et. al. (© 2008). Williams Textbook of Endocrinology, 11th Edition: Saunders Elsevier, Philadelphia, PA. Pp 1399.
Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL eds (2005). Harrison's Principles of Internal Medicine, 16th Edition, McGraw Hill, Pg 2156.
Matti Ankelo, et al. Time-Resolved Immunofluorometric Dual-Label Assay for Simultaneous Detection of Autoantibodies to GAD65 and IA-2 in Children with Type 1 Diabetes. Clinical Chemistry. 2007;53:472-479.
Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007, 956.
Sources Used in Previous Reviews
Maclaren, N. and Marker, J. (2002 December). Guidelines & Recommendations for Laboratory Analysis in the Diagnosis & Management of Diabetes Mellitus. Weill College of Medicine of Cornell University, NACB Laboratory Medicine Practice Guidelines [On-line information]. Available online at http://www.nacb.org/temporary/Maclaren2.htm through http://www.nacb.org.
Kimpimäki, T. et. al. (2000). Disease-Associated Autoantibodies as Surrogate Markers of Type 1 Diabetes in Young Children at Increased Genetic Risk. Journal of Clinical Endocrinology & Metabolism Vol 85 No. 3 1126-1132 [On-line information]. Available online at http://jcem.endojournals.org/cgi/content/full/85/3/1126 through http://jcem.endojournals.org.
Borg, H. et. al. (2001). High Levels of Antigen-Specific Islet Antibodies Predict Future ß-Cell Failure in Patients with Onset of Diabetes in Adult Age. The Journal of Clinical Endocrinology & Metabolism 86 (7): 3032. (2001) [On-line journal]. Available online at http://jcem.endojournals.org/cgi/reprint/86/7/3032 through http://jcem.endojournals.org.
Achenbach, P. et. al. (2004). Stratification of Type 1 Diabetes Risk on the Basis of Islet Autoantibody Characteristics. Diabetes 53:384-392 [On-line journal]. Available online at http://diabetes.diabetesjournals.org/cgi/content/full/53/2/384 through http://diabetes.diabetesjournals.org.
(© 2005). Glutamic Acid Decarboxylase (GAD) Antibody. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_a287.jsp#1149613 through http://www.arup-lab.com.
(© 2005). Islet Cell Antibody, IgG. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_a25b.jsp#1153005 through http://www.arup-lab.com.
(© 2005). IA-2 Antibody. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_alpb.jsp#2441172 through http://www.arup-lab.com.
Dupré, J. & Mahon, J. (2000 August). Diabetes-Related Autoantibodies and the Selection of Subjects for Trials of Therapies to Preserve Pancreaticß-Cell Function in Recent-Onset Type 1 Diabetes. Diabetes Care, (23): 8 [On-line information]. Available online through http://care.diabetesjournals.org.
Rewers, M. (2005 October, Updated). Type I Diabetes: Molecular, Cellular, and Clinical Immunology, Chapter 9 Epidemiology of Type I Diabetes. Barbara Davis Center for Childhood Diabetes, UCDHSC [On-line information]. Available online at http://www.uchsc.edu/misc/diabetes/oxch9.html through http://www.uchsc.edu.
Eisenbarth, G. (2003 November). Chapter 11 Prediction of Type I Diabetes: The Natural History of the Prediabetic Period. Type I Diabetes: Molecular, Cellular, and Clinical Immunology, Barbara Davis Center for Childhood Diabetes, UCDHSC [On-line information]. Available online at http://www.uchsc.edu/misc/diabetes/oxch11.html through http://www.uchsc.edu.
Winter, WE. Diabetes disease management: differentiating type 1 and type 2 diabetes. Clinical Laboratory News. 2005; 31(7):14-16.
Winter, W.E. Autoimmune Disorders that Influence Carbohydrate Metabolism (Chapter 24). In: Clinical and Laboratory Evaluation of Human Autoimmune Diseases. Nakamura R.M., Keren, D.F., Bylund D.J. (eds): ASCP Press, Chicago, 2002, Pp:345-372.
Winter, W.E. Autoimmune Endocrinopathies. In: Pediatric Endocrinology, Fourth Edition, F. Lifshitz (ed): Marcel Dekker, Inc., New York, New York, 2003, Pp 683-720.
Winter, W.E. and Signorino, M. R. Immunologic Disorders in Infants and Children (5th edition). In: Autoimmune Endocrinopathies. E.R. Stiehm (ed), W.B. Saunders Company, Philadelphia, Pennsylvania, 2004, Pp 1179-1221.
William Winter, M.D. Professor of Pathology and Pediatrics, University of Florida School of Medicine, Gainesville, FL.





