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Gonorrhea


Also known as: GC test
Formal name: Neisseria gonorrhoeae culture, Neisseria gonorrhoeae gram stain, Neisseria gonorrhoeae DNA probe, Neisseria gonorrhoeae by Amplified Detection
Related tests: Chlamydia

The Test Sample

What is being tested?

The test is looking for presence of the bacterium Neisseria gonorrhoeae, which causes the sexually transmitted disease gonorrhea. The Centers for Disease Control and Prevention (CDC) estimates that more than 700,000 people in the U.S. get new gonorrheal infections each year, but only half of these infections get reported to the CDC. In the US, the highest reported rates of infection are among sexually active teenagers, young adults, and African Americans.

Gonorrhea is generally transmitted through sexual contact (oral, vaginal, or anal) with an infected partner. An infected mother can pass the disease to her baby during childbirth.

While many men with gonorrhea will experience symptoms, most women do not, or they are mistaken for a bladder or other vaginal infection. For men, symptoms usually appear within 2 to 5 days of infection, but can take up to 30 days; for women, those who have symptoms usually experience them within 10 days of infection. Symptoms include, for females, burning or painful urination, increased vaginal discharge, and sometimes bleeding between menstrual periods or brought on by vaginal intercourse. For men, symptoms include a white, yellow or green discharge from the penis, a burning sensation when urinating, and sometimes painful or swollen testicles. Symptoms of rectal infection include discharge, itching, and painful bowel movements.

Gonorrhea can be treated with a course of antibiotics. Untreated gonorrhea can lead to severe complications. Women can develop pelvic inflammatory disease (PID), an infection that spreads from the vagina and cervix to the uterus and fallopian tubes. PID can cause scaring of the fallopian tubes, which can lead to ectopic pregnancy or infertility. In men, the infection can lead to an inflammation of the testicles that can result in sterility. In both males and females, the bacteria can also spread to the bloodstream and infect the joints, causing a type of arthritis. Other potentially severe clinical complications include osteomyelitis, meningitis, endocarditis, adult respiratory distress syndrome (ARDS), and fatal septic shock. A newborn infected with gonorrhea can develop blood, joint, and eye infections that can lead to blindness if not treated.

How is the sample collected for testing?

A swab is used to get a sample of secretion or discharge from the infected area such as the cervix, urethra, penis, anus, or throat. A urine sample is used in some tests. Many doctors will take a sample from more than one body site to increase the likelihood of finding the bacteria.

NOTE: If undergoing medical tests makes you or someone you care for anxious, embarrassed, or even difficult to manage, you might consider reading one or more of the following articles: Coping with Test Pain, Discomfort, and Anxiety, Tips on Blood Testing, Tips to Help Children through Their Medical Tests, and Tips to Help the Elderly through Their Medical Tests.

Another article, Follow That Sample, provides a glimpse at the collection and processing of a blood sample and throat culture.

Is any test preparation needed to ensure the quality of the sample?

No test preparation is needed.