Drug Category

Drugs in that Category

Treatment Use

Cardiac drugs         

Digoxin, digitoxin, quinidine, procainamide, N-acetyl-procainamide (a metabolite of procainamide)

Congestive heart failure, angina, arrhythmias

Antibiotics

Aminoglycosides (gentamicin, tobramycin, amikacin)Vancomycin, Chloramphenicol

Infections with bacteria that are resistant to less toxic antibiotics

Antiepileptics

Phenobarbital, phenytoin, valproic acid, carbamazepine, ethosuximide, sometimes gabapentin, lamotrigine

Epilepsy, prevention of seizures, sometimes to stabilize moods

Bronchodilators

Theophylline, caffeine

Asthma, Chronic obstructive pulmonary disorder (COPD), neonatal apnea

Immunosuppressants

Cyclosporine, tacrolimus, sirolimus, mycophenolate mofetil, azathioprine

Prevent rejection of transplanted organs, autoimmune disorders

Anti-cancer drugs

Methotrexate

Psoriasis, rheumatoid arthritis, various cancers, non-hodgkin's lymphomas, osteosarcoma

Psychiatric drugs

Lithium, valproic acid, some antidepressants (imipramine, amitriptyline, nortriptyline, doxepin, desipramine)

Bipolar disorder (manic depression), depression

Protease inhibitors

Indinavir, ritonavir, lopinavir, saquinavir, atazanavir, nelfinavir