| Cardiac drugs |
Digoxin, digitoxin, quinidine, procainamide, N-acetyl-procainamide (a metabolite of procainamide) |
Congestive heart failure, angina, |
| Antibiotics |
Aminoglycosides (gentamicin, tobramycin, amikacin), Vancomycin, Chloramphenicol |
Infections with that are resistant to less toxic antibiotics |
| Antiepileptics |
Phenobarbital, phenytoin, valproic acid, carbamazepine, ethosuximide, sometimes gabapentin, lamotrigine, levetiracetam, topiramate, zonisamide, eslicarbazepine acetate, felbamate, lacosamide, oxcarbazepine, pregabalin, rufinamide, stiripentol, tiagabine, vigabatrin |
Epilepsy, prevention of seizures, sometimes to stabilize moods |
| Bronchodilators |
Theophylline, caffeine |
Asthma, Chronic obstructive pulmonary disorder (COPD), |
| Immunosuppressants |
Cyclosporine, tacrolimus, sirolimus, mycophenolate mofetil, azathioprine |
Prevent rejection of transplanted organs, autoimmune disorders |
| Anti-cancer drugs |
Methotrexate |
Psoriasis, rheumatoid arthritis, various cancers, non-hodgkin's lymphomas, osteosarcoma |
| Psychiatric drugs |
Lithium, valproic acid, some antidepressants (imipramine, amitriptyline, nortriptyline, doxepin, desipramine) |
Bipolar disorder (manic depression), depression |
| Protease inhibitors |
Indinavir, ritonavir, lopinavir, saquinavir, atazanavir, nelfinavir |
HIV/AIDS |
