Adrenal Insufficiency and Addison Disease

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Tests: ACTH, Aldosterone and Renin, Cortisol, Electrolytes, Potassium, Glucose, BUN, Creatinine, Androstenedione
Conditions: Endocrine System and Syndromes, Autoimmune Disorders, Tuberculosis

Elsewhere On The Web
American Academy of Family Physicians: Addison's Disease  
MedlinePlus Medical Encyclopedia: Addison's Disease 
NIDDK: National Endocrine and Metabolic Diseases Information Service
National Adrenal Diseases Foundation
Society for Endocrinology: What do I need to know about adrenal insufficiency?

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

(Updated April 6, 2012). Adrenal insufficiency and Addison’s Disease. National Institutes of Health. Available online at http://endocrine.niddk.nih.gov/pubs/addison/addison.aspx accessed through http://endocrine.niddk.nih.gov/. Accessed on 19 Sept. 2012.

(Reviewed December 11, 2011). Addison’s Disease. PubMed Health. Available online at http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001416/ through http://www.ncbi.nlm.nih.gov. Accessed on 19 Sept. 2012.

(July 17, 2010). Addison’s Disease. Mayo Clinic. Available online at http://www.mayoclinic.com/health/addisons-disease/DS00361/DSECTION=tests-and-diagnosis through http://www.mayoclinic.com. Accessed on 19 Sept. 2012.

(Reviewed March 21, 2012) WebMD. Understanding Addison’s Disease. Availale online at http://www.webmd.com/a-to-z-guides/understanding-addisons-disease-basics through http://emedicine.medscape.com. Accessed on 19 Sept. 2012.

Pituitary Network Association. Adrenal Insufficiency. Available online at https://www.pituitary.org/disorders/addisons_disease.aspx through https://www.pituitary.org. Accessed on 19 Sept. 2012.

21-hydroxylase autoantibodies. Mayo Medical Laboratories. Available online at http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/81970 through http://www.mayomedicallaboratories.com. Accessed on 19 Sept. 2012.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

(2001). Addison's Disease: Diagnosis Can Be More Difficult Than Treatment. Drug Ther Perspect 17(8):12-15 [On-line journal]. Available online at http://www.medscape.com/viewarticle/406491 through http://www.medscape.com.

Alevritis, E et.al. (2003). South Med J 96(9): 888-890 [On-line journal]. Available online at http://www.medscape.com/viewarticle/462327 through http://www.medscape.com.

Graves, L., et. al. (2003 September 16). Addisonian Crisis Precipitated by Thyroxine Therapy: A Complication of Type 2 Autoimmune Polyglandular Syndrome. South Med J 96(8):824-827 [On-line information]. Available online at http://www.medscape.com/viewarticle/460531 through http://www.medscape.com.

(2002 September 11). Addison's disease. MayoClinic.com [On-line information]. Available online at http://www.mayoclinic.com/invoke.cfm?objectid=9C76354B-0F14-4ED1-A2A3358550A16E76%22 through http://www.mayoclinic.com.

Corrigan, E. (1998 February 12). Addison's Disease. NIH Publication No. 90-3054 [On-line information]. Available online at http://www.niddk.nih.gov/health/endo/pubs/addison/addison.htm through http://www.niddk.nih.gov.

(2002 April 3, Reviewed). What is Addison disease? MedicineNet.com [On-line information]. Available online at http://www.medicinenet.com/Addison_Disease/article.htm through http://www.medicinenet.com.

Lehnert, P. (2002 November 25, Updated). Addison's Disease. WebMD [On-line information]. Available online through http://my.webmd.com.

Brown, T. (2002 March 14). Medical Encyclopedia: ACTH (Cortrosyn) stimulation test. MedlinePLUS [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003696.htm.

Fish, S. (2002 May 10). Medical Encyclopedia: Acute adrenal crisis. MedlinePLUS [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000357.htm.

Brown, T. (2002 September 1). Medical Encyclopedia: Addison’s disease. MedlinePLUS [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000378.htm.

Corrigan, E. Adrenal Insufficiency (Secondary Addison's). NIH Publication No. 90-3054 Pituitary Network Association [On-line information]. Available online at http://www.pituitary.org/disorders/addisons.php through http://www.pituitary.org.

Adrenal Gland Disorders. Merck Manual Home Edition [On-line information]. Available onlne at http://www.merck.com/mrkshared/mmanual_home/sec13/146.jsp through http://www.merck.com.

Addison’s Disease. Merck Manual-2nd Home Edition [On-line information]. Available online at http://www.merck.com/pubs/mmanual_home2/sec13/ch164/ch164b.htm through http://www.merck.com.

Understanding Addison's Disease -- the Basics. WebMD Health [On-line information]. Available online at http://my.webmd.com/content/article/7/1680_53715 through http://my.webmd.com.

Holt, E. (Updated 2008 March 18). Addison's Disease. MedlinePlus Medical Encyclopedia. [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000378.htm. Accessed March 2009.

Grossman, A. (Revised 2007 November). Secondary Adrenal Insufficiency. Merck Manual for Healthcare Professionals. [On-line information]. Available online at http://www.merck.com/mmpe/sec12/ch153/ch153c.html through http://www.merck.com. Accessed March 2009.

Grossman, A. (Revised 2007 November). Addison's Disease (Primary or Chronic Adrenocortical Insufficiency). Merck Manual for Healthcare Professionals. [On-line information]. Available online at http://www.merck.com/mmpe/sec12/ch153/ch153b.html?qt=addisons&alt=sh through http://www.merck.com. Accessed March 2009.

Klauer, K. (Updated 2008 August 19). Adrenal Insufficiency and Adrenal Crisis. eMedicine from WebMD. [On-line information]. Available online at http://emedicine.medscape.com/article/765753-overview through http://www.emedcine.medscape.com. Accessed March 2009.

Mayo Clinic Staff. (2008 June 17). Addison's Disease. MayoClinic.com. [On-line information]. Available online at http://www.mayoclinic.com/print/addisons-disease/DS00361/DSECTION=all&METHOD=print through http://wwwmayoclinic.com. Accessed March 2009.

Shulman, D. et al. Adrenal Insufficiency: Still a Cause of Morbidity and Death in Childhood. Pediatrics Vol. 119 No. 2 February 2007, Pp. e484-e494. Available online at http://pediatrics.aappublications.org/cgi/content/full/119/2/e484 through http://pediatrics.aappublications.org. Accessed January 2011.

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