Alzheimer Disease

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On This Site
Tests: APOE Genotyping, PSEN1, Tau/Aß42
In the News: Blood Test Shows Very Preliminary Results in Predicting Alzheimer Disease (2014), Biomarkers Incorporated Into Alzheimer's Disease Diagnostic Criteria (2011)

Elsewhere On The Web

Specifically concerning Alzheimer disease
National Institute of Neurological Disorders and Stroke: Alzheimer's Disease Information Page
Our Alzheimer's.com: Support Groups
Alzheimer Research Forum
Alzheimer's Disease Education and Referral (ADEAR) Center
ADEAR Center: Alzheimer's Disease, Unraveling the Mystery
Bright Focus Foundation: About Alzheimer's
Alzheimer Society of Canada
National Institute on Aging: Alzheimer's Disease Fact Sheet

Alzheimer's Association: Latest Alzheimer's Disease Facts and Figures

General elder care, including Alzheimer disease
National Resource Center on Aging and Injury
USA.gov: Senior Citizens' Resources

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

(April 1, 2013) Stetka B. Alzheimer Biomarkers in Clinical Practice. Medscape Today. Available online at http://www.medscape.com/viewarticle/781533 through http://www.medscape.com. Accessed March 2014.

Anderson, H. (Updated 2014 March 3). Alzheimer Disease. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/1134817-overview through http://emedicine.medscape.com. Accessed March 2014.

Small, G. (Updated 2012 February 8). Alzheimer Disease and APOE-4. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/1787482-overview#showall through http://emedicine.medscape.com. Accessed March 2014.

Alvarez, N. (Updated 2012 March 2). Alzheimer Disease in Down Syndrome. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/1136117-overview#showall through http://emedicine.medscape.com. Accessed March 2014.

Anderson, P. (2013 March 21). 1 in 3 Seniors Dies With Alzheimer's or Other Dementia. Medscape Today News [On-line information]. Available online at http://www.medscape.com/viewarticle/781180 through http://www.medscape.com. Accessed March 2014.

(2013 January 14). 2011-2012 Alzheimer's Disease Progress Report. Alzheimer's Disease Education and Referral Center [On-line information]. Available online at http://www.nia.nih.gov/alzheimers/publication/2011-2012-alzheimers-disease-progress-report/ through http://www.nia.nih.gov. Accessed March 2014.

(Reviewed 2012 December). Alzheimer's Disease. NIHSeniorHealth [On-line information]. Available online at http://nihseniorhealth.gov/alzheimersdisease/whatisalzheimersdisease/01.html through http://nihseniorhealth.gov. Accessed March 2014.

(Updated 2014 February 20). Alzheimer's Disease: Unraveling the Mystery. Alzheimer's Disease Education and Referral Center [On-line information]. Available online at http://www.nia.nih.gov/alzheimers/publication/alzheimers-disease-unraveling-mystery through http://www.nia.nih.gov. Accessed March 2014.

Mayo Clinic Staff (2011 March 31) Early-onset Alzheimer's: When symptoms begin before age 65. Mayo Clinic [On-line information]. Available online at http://www.mayoclinic.com/print/alzheimers/AZ00009/METHOD=print through http://www.mayoclinic.com. Accessed March 2014.

(© 2014) What We Know Today About Alzheimer's Disease. Alzheimer’s Association [On-line information]. Available online at http://www.alz.org/research/science/alzheimers_disease_causes.asp#chromosomes through http://www.alz.org. Accessed March 2014.

McKhann, G. et. al. (2011 April 22). The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimer's & Dementia 7 (2011) 263–269 [On-line information]. Available online at http://www.alzheimersanddementia.com/article/S1552-5260(11)00101-4/abstract through http://www.alzheimersanddementia.com. Accessed March 2014.

Leslie M Shaw, PhD. Director, Toxicology Laboratory, Biomarker Research Laboratory, Department of Pathology & Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Sloane, P. (1998, November 1). Advances in the Treatment of Alzheimer's Disease. American Family Physician by the American Academy of Family Physicians [On-line journal]. Available online at http://www.aafp.org/afp/981101ap/sloane.html through http://www.aafp.org.

Eastman, P. (2002 March). Keeping Alzheimer's at Bay, Early Diagnosis Keeps Patients Functioning Longer. AARP Bulletin Online [On-line serial]. Available online at http://www.aarp.org/bulletin/departments/2002/health/0310_health_1.html through http://www.aarp.org.

McConnell, S., et. al. Unraveling the Mysteries of Alzheimer's Disease: Exciting New Developments in Research. From panel sponsored by the Alzheimer's Association [On-line information]. Available online at http://www.asaging.org/am/cia2/alzheimer.html through http://www.asaging.org.

Galasko, D., et. al. (1998). High Cerebrospinal Fluid Tau and Low Amyloid b42 Levels in the Clinical Diagnosis of Alzheimer Disease and Relation to Apolipoprotein E Genotype. Arch Neurol [On-line journal], vol (55) pages (937-945). Available online at http://archneur.ama-assn.org/issues/v55n7/abs/noc7433.html through http://archneur.ama-assn.org.

ARF (1996-2002). Standard Medical Workup for Alzheimer's Disease. Alzheimer Research Forum [On-line information]. Available online at http://www.alzforum.org/members/research/treatment_guide/workup.html through http://www.alzforum.org.

Family Caregiver Alliance. Fact Sheet: Alzheimer's Disease [On-line information]. Available online at http://www.caregiver.org/factsheets/diagnoses/alzheimersC.html through http://www.caregiver.org.

Bird, T. (2001 June 22 last update). Alzheimer Overview. GeneReviews [On-line information]. Available online through http://www.genetests.org.

Gottlieb, F. and Lambert, J. G. (2002, January 2, last update). Alzheimer’s Disease. MEDLINEplus [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000760.htm.

Miller, M. (1998 February 18). 26 national Alzheimer's Disease Centers Collaborate on Study of the Utility of Genetic Testing for Alzheimer's. National Institutes of Health News Release [On-line press release]. Available online at http://www.nia.nih.gov/news/pr/1998/02%2D18.htm through http://www.nia.nih.gov.

NIH (2000). Progress report on Alzheimer's disease, taking the next steps. NIH Publication No. 00-4859 [On-line report]. Available online at http://www.alzheimers.org/pubs/prog00.htm#Introduction through http://www.alzheimers.org.

UniSci (2002, April 08). New Approaches Seen For Early Alzheimer’s Diagnosis. Daily University Science News [On-line Article]. Review of two studies found in Neuropsychology, Vol 16 (2). Available online at http://unisci.com/stories/20022/0408025.htm through http://unisci.com.

Eldercare (2002 February 28, last update). Is it Alzheimer's ...or Just Forgetfulness? Sponsored by Nebraska's Area Agencies on Aging [On-line information]. Available online at http://nncf.unl.edu/eldercare/info/lifeline/LLforget.html through http://nncf.unl.edu.

Hain, T. (2000 February 13). Alzheimer's Disease. Neurology, Northwestern University Medical School [3rd year neurology medical student curriculum material]. Available online at http://www.neuro.nwu.edu/meded/behavioral/alzheimers.html through http://www.neuro.nwu.edu.

Kleiner-Fisman, G., Updated by (2002 January 2, last update). CSF Collection. MEDLINEplus [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003428.htm.

Boston University Medical Center, Clinical Research & Resource Center: Alzheimer’s Disease, Brain Tissue Donation. Available online at http://www.bu.edu/alzresearch/brain_tissue_don.htm through http://www.bu.edu.

Michigan Alzheimer's Disease Research Center. Available online at http://www.med.umich.edu/madrc/supplemental.html through http://www.med.umich.edu.

Robert C. Green, M.D., M.P.H. Professor of Neurology, Genetics and Epidemiology. Director, Alzheimer's Disease Clinical and Research Program. Boston University Schools of Medicine and Public Health, Boston, MA.

Ian R.A. Mackenzie, MD FRCPC. Department of Pathology, Vancouver General Hospital, British Columbia, Canada.

Anderson, H. and Kuljis, R. (2008 November 24). Alzheimer Disease. EMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/1134817-overview through http://emedicine.medscape.com. Accessed April 2009.

Alvarez, N. (Updated 2008 January 10). Alzheimer Disease in Individuals With Down Syndrome. EMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/1136117-overview through http://emedicine.medscape.com. Accessed April 2009.

(Updated 2009 February 24) Alzheimer's Disease Fact Sheet. National Institute on Aging, Alzheime's Disease Education & Referral Center [On-line information]. Available online at http://www.nia.nih.gov/Alzheimers/Publications/adfact.htm through http://www.nia.nih.gov. Accessed April 2009.

(2009 March 17). Scientists Report Important Step in Biomarker Testing for Alzheimer's Disease. National Institute on Aging, Alzheimer’s Disease Education & Referral Center [On-line information]. Available online at http://www.nia.nih.gov/Alzheimers/ResearchInformation/NewsReleases/PR20090317biomarkers through http://www.nia.nih.gov. Accessed April 2009.

Brown Rodgers, A. (2008 September). Alzheimer's Disease: Unraveling the Mystery. National Institute on Aging, Alzheimer's Disease Education & Referral Center [On-line information]. Available online at http://www.nia.nih.gov/Alzheimers/Publications/Unraveling/ through http://www.nia.nih.gov. Accessed April 2009.

(2009). 2009 Alzheimer's Disease Facts and Figures. Alzheimer's Association [On-line information]. PDF available for download at http://www.alz.org/national/documents/report_alzfactsfigures2009.pdf through http://www.alz.org. Accessed April 2009.

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