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Breast Cancer

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Tests: BRCA1 and BRCA2, Tumor Markers, CA 15-3, HER2/neu, Estrogen/Progesterone Receptor Status, Breast Cancer Multiparameter Gene Expression Tests
Screening: Young Adults (19-29), Adults (30-49), Adults (50 and up)
In the News: Should All Women Be Screened for BRCA Mutations that Increase Breast Cancer Risk? (2014), New Study Finds Mutations in PALB2 Gene Increase Lifetime Risk of Breast Cancer (2014), New CDC Resource Helps Women Understand BRCA Gene Mutation Risk for Breast and Ovarian Cancer (2014), Cancer Groups Release New Guideline on HER2 Testing for Breast Cancer Patients (2013), U.S. Supreme Court Invalidates BRCA Patent (2013), Angelina Jolie's Announcement Heightens Interest in BRCA, But This Testing Is Not for Everyone (2013), AMA Modifies Guidelines for Breast Cancer Screening (2012), CRP May Have Role in Predicting Breast Cancer Outcomes (2011), Advancements Being Made in Methods to Detect Circulating Tumor Cells for Cancer Treatment (2011)

Elsewhere On The Web
American Cancer Society: Breast Cancer Overview
Genetic Health: Considering Genetic Testing
National Cancer Institute: Breast Cancer
College of American Pathologists: MyBiopsy.org
OncologySTAT: Breast Cancer Resources
American Academy of Family Physicians: Breast Cancer, Steps to Finding Breast Lumps Early 
National Cancer Institute: What You Need to Know About Breast Cancer 
National Cancer Institute: Breast Cancer Risk Assessment Tool 
National Human Genome Research Institute: Learning About Breast Cancer 
Centers for Disease Control and Prevention: Breast Cancer 
Acrobat-Reader_logo.gifCenters for Disease Control and Prevention: Breast Cancer and You 
Acrobat-Reader_logo.gifNational Comprehensive Cancer Network: NCCN Guidelines for Patients, Breast Cancer 

 

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review.

Sources Used in Current Review

(Modified 2011 July 27). Breast Cancer Screening (PDQ®). National Cancer Institute [On-line information]. Available online at http://www.cancer.gov/cancertopics/pdq/screening/breast/healthprofessional through http://www.cancer.gov. Accessed July 2011.

(Modified 2011 July 14). Breast Cancer Treatment (PDQ®). National Cancer Institute [On-line information]. Available online at http://www.cancer.gov/cancertopics/pdq/treatment/breast/healthprofessional through http://www.cancer.gov. Accessed July 2011.

Barclay, L. (2011 July 20). ACOG Recommends Annual Mammograms Begin at Age 40 Years. Medscape Medical News [On-line information]. Available online at http://www.medscape.com/viewarticle/746754 through http://www.medscape.com. Accessed July 2011.

(Revised 2011 February 9). Breast Cancer Detailed Guide. American Cancer Society [On-line information]. Available online at http://www.cancer.org/Cancer/BreastCancer/DetailedGuide/index through http://www.cancer.org. Accessed July 2011.

(Revised 2010 September 16). Inflammatory Breast Cancer. American Cancer Society [On-line information]. Available online at http://www.cancer.org/Cancer/BreastCancer/MoreInformation/InflammatoryBreastCancer/index through http://www.cancer.org. Accessed July 2011.

(Updated 2011 June 9). Basic Information About Breast Cancer. Centers for Disease Control and Prevention [On-line information]. Available online at http://www.cdc.gov/cancer/breast/basic_info/ through http://www.cdc.gov. Accessed July 2011.

Mayo Clinic Staff (2011 May 7). Breast Cancer. Mayo Clinic [On-line information]. Available online at http://www.mayoclinic.com/health/breast-cancer/DS00328 through http://www.mayoclinic.com. Accessed July 2011.

Mayo Clinic Staff (2010 February 3). Inflammatory Breast Cancer. Mayo Clinic [On-line information]. Available online at http://www.mayoclinic.com/health/inflammatory-breast-cancer/DS00632 through http://www.mayoclinic.com. Accessed July 2011.

(2011 July 20). Annual Mammograms Now Recommended for Women Beginning at Age 40. ACOG Press Release [On-line information]. Available online at http://www.acog.org/from_home/publications/press_releases/nr07-20-11-2.cfm through http://www.acog.org. Accessed August 2011.

Sources Used in Previous Reviews

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 198-199.

Clarke, W. and Dufour, D. R., Editors (2006). Contemporary Practice in Clinical Chemistry, AACC Press, Washington, DC. Pp 243-244.

Harris, L. et. al. (2007 November 20). American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer. Journal of Clinical Oncology v25(33) [On-line journal article]. Available online through http://jco.ascopubs.org. Accessed on 12/9/07.

(2007 May 14). Test Determines Risk of Breast Cancer Returning. FDA Consumer Update [On-line information]. Available online through http://www.fda.gov. Accessed on 12/9/07.

(© 2007). Oncotype DX FAQ. Genomic Health [On-line information]. Available online at http://www.genomichealth.com/oncotype/faq/hcp.aspx through http://www.genomichealth.com. Accessed on 12/9/07.

(© 2007). About Oncotype DX. Genomic Health [On-line information]. Available online at http://www.genomichealth.com/oncotype/about/hcp.aspx through http://www.genomichealth.com. Accessed on 12/9/07.

FDA clears MammaPrint test for marketing. News-Medical.Net [On-line information]. Available online through http://www.news-medical.net. Accessed on 12/9/07.

(© 2007). MammaPrint for Professionals. Agendia [On-line information]. Available online through http://www.agendia.com. Accessed on 12/9/07.

Detailed Guide: Breast Cancer. American Cancer Society [On-line information]. Available online through http://www.cancer.org. Accessed on 12/9/07.

Barr, H. et. al. (2007 May 31). Breast Cancer Module I: Breast Anatomy, Physiology, and Pathology CME/CE. Medscape CME [On-line information]. Available online through http://www.medscape.com. Accessed on 12/9/07.

(2007 October 10). Breast Cancer Statistics. CDC [On-line information]. Available online http://www.cdc.gov/cancer/breast/statistics/ through http://www.cdc.gov. Accessed on 12/9/07.

National Comprehensive Cancer Network Practice Guidelines in Oncology, v.2.2008 (online information). PDF available for download at http://www.nccn.org/. Accessed January 2008.

Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement. U.S. Preventive Services Task Force. Annals of Internal Medicine. November 17, 2009 vol. 151 no. 10 716-726. Available online at http://www.annals.org/content/151/10/716.full through http://www.annals.org. Accessed November 2009.

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