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Cushing Syndrome

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Signs and Symptoms

Signs and symptoms associated with Cushing syndrome vary but frequently include:

  • Obesity in the torso (central obesity) with thinner arms and legs
  • A large rounded face (moon face)
  • Increased fat in the neck and shoulder area (Buffalo hump)
  • Thirst and excessive urination
  • Visual problems caused by glaucoma or cataracts
  • Increased susceptibility to infections
  • Thin, fragile skin that bruises easily and heals slowly
  • Pinkish streaks that look like stretch marks on the abdomen, thighs, and buttocks
  • Muscle weakness
  • Decreased endurance
  • Osteoporosis
  • High blood pressure
  • Increased blood sugar
  • Headaches, backaches
  • Mental symptoms (confusion to psychosis)
  • Children with Cushing syndrome tend to be obese, develop slowly, and may remain short.
  • Women may have excess hair on their face and chest and menstrual irregularities.
  • Men may have decreased sexual desire or impotence.

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