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Liver Disease

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Types of Liver Disease

Type of Liver Disease Description Examples of Causes/Conditions
Acute liver failure Rapid decrease in liver function Drugs, toxins, a variety of liver diseases
Alcoholic liver disease Liver damage due to alcohol that can lead to fatty liver disease, alcoholic hepatitis, or cirrhosis Excessive consumption of alcohol over time
Autoimmune-associated The body produces an inappropriate immune response against itself; sometimes develops antibodies against own liver tissue PBC (Primary biliary cirrhosis), PSC (Primary sclerosing cholangitis), Autoimmune hepatitis
Budd-Chiari syndrome Blood clots impede blood flow from the liver; symptoms such as ascites, enlarged liver, jaundice, and abdominal pain can develop Hypercoagulable disorders, liver injury, cancer, parasitic infection
Cirrhosis Scarring of liver tissue leads to decreased liver function Can be caused by a variety of conditions but usually a result of chronic hepatitis, alcoholism, or chronic bile duct obstruction
Genetic Gene mutations can lead to liver damage, disease; relatively rare conditions Hemochromatosis, Alpha-1 antitrypsin deficiency, Wilson disease
Hepatitis Acute or chronic liver inflammation Viruses, alcohol abuse, drugs, toxins, autoimmune, nonalcoholic fatty liver disease (NAFLD)
Infections Certain infections can cause various degrees of liver damage, blockage of bile ducts Viral hepatitis, parasitic infection
Liver cancer A cancer that originates in the liver Increased risk with cirrhosis and chronic hepatitis; hepatocellular carcinoma (HCC) is most common primary liver tumor
Obstruction of bile ducts Complete or partial blockage of bile ducts Tumors, gallstones, inflammation, trauma

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