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Lymphoma
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The following table illustrates the two most commonly used classifications plus an older classification. Because of differences in how the lymphomas are described, there is not a one-to-one comparison between the systems, and a single disease could be known by multiple names.
Comparison of Some Non-Hodgkin Lymphoma Classifications
Note: These classifications cannot always be compared
| NCI* (Working Formulation) (Older Classification) |
REAL** |
WHO*** Classification |
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B cell lineage/NHL |
Mature B cell lymphoma |
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Low grade lymphoma Small lymphocytic lymphoma Small lymphocytic lymphoma (plasmacytoid)
Follicular lymphoma (small cleaved cell, large cell, mixed cell)
High Grade lymphoma Diffuse lymphoma (small cleaved, large, mixed cell) Diffuse immunoloblastic lymphoma Burkitt Lymphoma Burkitt-like Lymphoma Lymphoblastic lymphoma |
B-cell chronic lymphocytic leukemia Lymphoplasmacytic lymphoma Nodal and extranodal marginal B-cell lymphoma
Follicular Center, grades I, II, and III lymphoma
Mantle Cell lymphoma |
B cell CLL / SLL Splenic marginal zone B-cell lymphoma Extranodal marginal B cell lymphoma
Follicular lymphoma
Mantle cell lymphoma
Diffuse large B-cell lymphoma
Burkitt’s lymphoma |
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T and NK Cell Neoplasms |
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T and NK Cell Neoplasms |
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Mature T cell lymphoma |
Small lymphocyte lymphoma
Mycosis Fungoides
Diffuse lymphoma (small cleaved, large, mixed cell)
Large cell immunoblastic lymphoma |
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Adult T cell lymphoma
Mycosis fungoides (S�zary Syndrome)
Anaplastic large cell lymphoma not otherwise characterized
Immunoblastic T cell lymphoma |
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Langerhans cell histiocytosis
Langerhans cell sarcoma
Interdigitating dendritic cell sarcoma/tumor
Follicular dendritic cell sarcoma/tumor
Dendritic cell sarcoma, not otherwise specified |
* NCI = National Cancer Institute
** REAL = Revised European American Lymphoma
*** WHO = World Health Organization
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Related Pages
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This article last reviewed on February 14, 2007.
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