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Pancreatic Insufficiency

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Tests: Trypsin and Chymotrypsin, Fecal Fat
Conditions: Pancreatic Diseases, Pancreatic Cancer, Pancreatitis, Cystic Fibrosis, Diabetes, Endocrine Syndromes

Elsewhere On The Web
Pancreas.org
National Digestive Diseases Information Clearinghouse: ERCP
National Digestive Diseases Information Clearinghouse: Zollinger-Ellison Syndrome
Shwachman-Diamond Syndrome Foundation: Understanding SDS

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Al-Kaade, Samer, et. al. (Updated Jan. 29, 2013.) Exocrine Pancreatic Insufficiency. Medscape. Available online at http://emedicine.medscape.com/article/2121028-overview#aw2aab6b2b4 through http://emedicine.medscape.com. Accessed March 2014.

Dominguez-Munoz, JE. (March 2011.) Pancreatic Exocrine Insufficiency: Diagnosis and Treatment. PubMed. Available online at http://www.ncbi.nlm.nih.gov/pubmed/21323992 through http://www.ncbi.nlm.nih.gov/pubmed. Accessed March 2014.

Lohr, J-Matthias, et. al. (Jan. 7, 2013.) Synopsis of Recent Guidelines on Pancreatic Exocrine Insufficiency. United European Gastroenterology Journal. Available online at http://ueg.sagepub.com/content/1/2/79 through http://ueg.sagepub.com. Accessed April 2014.

Dominguez-Munoz, JE, et. al. (April 2007.) 13C-Mixed Triglyceride Breath Test to Assess Oral Enzyme Substitution Therapy in Patients with Chronic Pancreatitis. PubMed. Available online at http://www.ncbi.nlm.nih.gov/pubmed/17445754 through http://www.ncbi.nlm.nih.gov/pubmed. Accessed April 2014.

Secretin Stimulation Test. (Updated Oct. 8, 2012.) MedlinePlus. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003892.htm through http://www.nlm.nih.gov/medlineplus. Accessed April 2014.

Exocrine Pancreatic Insufficiency. (Updated Apr. 1, 2014.) Aptalis. Available online at http://www.aptalispharma.com/epi through http://www.aptalispharma.com. Accessed April 2014.

Philip D. Hardt and Nils Ewald. Exocrine Pancreatic Insufficiency in Diabetes Mellitus: A Complication of Diabetic Neuropathy or a Different Type of Diabetes? Experimental Diabetes Research, Volume 2011, Article ID 761950.

Gregory C. Sephel PhD FACB MT(ASCP). Lab Tests Online adjunct board member. Director Clinical Pathology, VA TN Valley Healthcare System; Associate Professor Pathology, Microbiology, Immunology, Vanderbilt University School of Medicine.

Sources Used in Previous Reviews

Everhart, J. Digestive Diseases and Diabetes. Chapter 21 [pp 474-476]. NIDDK [On-line information]. PDF available for download at http://www.niddk.nih.gov/health/diabetes/dia/chpt21.pdf through http://www.niddk.nih.gov.

Merck. Malabsorption Syndromes, [General]. The Merck Manual of Diagnosis and Therapy [On-line information]. Available online at http://www.merck.com/pubs/mmanual/section3/chapter30/30a.htm through http://www.merck.com.

National Digestive Diseases Information Clearinghouse. ERCP (Endoscopic Retrograde Cholangiopancreatography). Available online at http://digestive.niddk.nih.gov/ddiseases/pubs/ercp/ through http://digestive.niddk.nih.gov.

Durie PR. Inherited and congenital disorders of the exocrine pancreas. Gastroenterologist. Sep 1996;4(3):169-87.

Mack DR, Forstner GG, Wilschanski M, Freedman MH, Durie PR. Shwachman syndrome: exocrine pancreatic dysfunction and variable phenotypic expression. Gastroenterology. Dec 1996;111(6):1593-602.

Spoto-Cannons, Antoinette C. Shwachman-Diamond Syndrome. Emedicine.com. Article Last Updated: Aug 12, 2008. Available online at http://www.emedicine.com/ped/TOPIC2060.HTM through http://www.emedicine.com.

Sharma, G. (Updated 2010 December 3). Cystic Fibrosis. eMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/1001602-overview through http://emedicine.medscape.com. Accessed January 2011.

Spoto-Cannons, A. et. al. (Updated 2009 September 30). Shwachman-Diamond Syndrome. eMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/958476-overview through http://emedicine.medscape.com. Accessed January 2011.

Delgado, J. et. al. (Updated 2010 November). Malabsorption. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/Malabsorption.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed January 2011.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 441-442.

RadiologyInfo.org. Endoscopic retrograde cholangiopancreatography (ERCP). Avaiable online at http://www.radiologyinfo.org/en/glossary/glossary1.cfm?gid=805 through http://www.radiologyinfo.org. Accessed January 2012.

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