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Sarcoidosis

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Treatment

There is no way to prevent or cure sarcoidosis, but in many cases it will resolve on its own over time. The goals of treatment are to relieve symptoms, decrease inflammation, and to minimize tissue and organ damage. People who have few or mild symptoms may not need treatment, but their condition should be monitored.

Those with moderate to severe symptoms and those at risk for tissue or organ damage are usually treated with corticosteroids such as prednisone. These anti-inflammatory medications may be given orally, topically, or through an inhaler. Long-term use of corticosteroids can cause significant side-effects.

Other medications may include:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen for pain and inflammation
  • Methotrexate and other drugs that suppress the immune system for lung, skin, or eye involvement
  • Hydroxychloroquine (an anti-malarial drug) may be useful for skin and nervous system involvement, especially in people who have increased calcium levels.

Most people can be successfully treated, but they may need to take medications for an extended period of time. Rarely, a person may need an organ transplant if the lungs or liver have become severely damaged.

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