Vitamin K Deficiency

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Signs and Symptoms

The signs and symptoms associated with vitamin K deficiency may include:

  • easy bruising
  • oozing from nose or gums
  • excessive bleeding from wounds, punctures, and injection or surgical sites
  • heavy menstrual periods
  • bleeding from the gastrointestinal (GI) tract
  • blood in the urine and/or stool
  • an increased prothrombin time (PT/INR)

In hemorrhagic disease of the newborn, signs and symptoms may be similar to those listed above, but in more serious cases may also involve bleeding within the skull (intracranial).

A deficiency of vitamin K may be suspected when symptoms listed above appear in someone who is at an increased risk such as:

  • those who have a chronic condition associated with malnutrition or malabsorption
  • those who have been on long-term treatment with antibiotics; the antibiotics can kill the bacteria that aid in the production of vitamin K2 in the small intestine.
  • seriously ill patients such as cancer or dialysis patients or those in intensive care units

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