This article waslast modified on July 10, 2017.
A disorder similar to diabetes mellitus in that it causes symptoms such as increased thirst and increased urine production, but differing in cause, frequency, treatment, and associated complications; diabetes insipidus results from a lack of production of arginine vasopressin (also called antidiuretic hormone or ADH) by the pituitary or a lack of response of the kidneys to ADH, causing an inability of the kidneys to conserve water. It can lead to severe dehydration and high serum sodium if inadequately treated. Diabetes inspididus is a much more rare condition than diabetes mellitus.