This article waslast modified on November 6, 2020.

Fusion genes are the result of chromosomes breaking and rejoining incorrectly so that two different genes are joined together. The new locations of the genes or the combination of the genes themselves may produce a new protein or effect. Often, the normal function of one of the genes involved is altered in such a way that it then promotes cell growth without responding to the normal checks and balances that cells use to stay healthy, which can lead to cancer.