This article waslast modified on November 30, 2017.

Also known as: Ig; Antibody; Immune serum globulin; Immune globulin; Gamma globulin

1) Special proteins produced by the body in response to foreign substances including bacteria and viruses; there are five structurally distinct classes of immunoglobulins produced by plasma cells in the bone marrow and other lymphoid tissue that bind to and neutralize foreign substances (antigens). The five major kinds of immunoglobulins are A, D, E, G and M.

2) A solution made from human blood plasma that contains concentrated antibodies that protect against specific diseases, such as short-term protection against certain infections and Rh sensitization during pregnancy; it is made from human blood plasma that has been pooled, processed from donated blood, and purified.