This article waslast modified on April 26, 2018.

Also known as hereditary nonpolyposis colon cancer or HNPCC.
An inherited condition that increases the risk of many types of cancer, especially colon cancer. People who inherit mutations in the MLH1, MSH2, MSH6, PMS2, or EPCAM gene have an increased risk of developing Lynch syndrome. Besides colon cancer, examples of other cancers associated with Lynch syndrome include cancers of the stomach, liver, bile ducts, brain, skin, ovaries and lining of the uterus (endometrium).