Concerned that certain cancers run in your family? Learn how BRCA gene mutation testing can answer questions about an individual’s inherited cancer risk.
CALR (calreticulin) gene mutations are associated with blood cancers called myeloproliferative neoplasms (MPNs) that cause the production of too many blood cells. The CALR mutation test helps diagnose and classify MPNs.
Factor V Leiden mutation and PT 20210 mutation tests determine whether you have inherited a gene mutation that increases your risk of developing a harmful blood clot, including a deep venous thrombosis (DVT) or venous thromboembolism (VTE)
Janus Kinase 2 (JAK2) gene mutations are associated with bone marrow disorders called myeloproliferative neoplasms (MPNs) caused by the production of too many blood cells. JAK2 mutation tests help diagnose MPNs.
Describes how epidermal growth factor receptor (EGFR) mutation testing is used, when EGFR mutation testing is ordered, and what the results of EGFR mutation testing might mean
The MTHFR mutation test may sometimes be ordered when a person has elevated homocysteine levels, especially when the person has a personal or family history of premature cardiovascular disease or thrombosis.
KRAS mutation testing is used to help guide treatment of metastatic colon cancer or non-small cell lung cancer. A tumor that has KRAS mutations may not respond to targeted cancer therapy.
Genetic tests for targeted cancer therapy detect mutations (changes) in the DNA of cancer cells. Knowing whether the cancer has a particular mutation can help guide the type of treatment that a person receives. The presence or absence of certain mutations can predict who may benefit from certain drugs and who is not likely to respond.
Describes how Anaplastic Lymphoma Receptor Tyrosine Kinase (ALK) mutation testing is used, when ALK mutation (gene rearrangement) testing is ordered, and what the results of ALK mutation testing might mean
