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ALK Mutation (Gene Rearrangement)

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Also known as: EML4-ALK Fusion Protein; ALK Gene Rearrangement; ALK Gene Fusion
Formal name: ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase) Gene Rearrangement

Were you looking instead for the Alkaline Phosphatase test, also known as ALK PHOS or ALP, used in the evaluation of liver or bone disease? If so, go to the ALP article.

At a Glance

Why Get Tested?

To detect an ALK gene rearrangement in tumor tissue in order to guide non-small cell lung cancer therapy

When to Get Tested?

When you have been diagnosed with non-small cell lung cancer and your doctor is considering a therapeutic management plan that may include an ALK kinase inhibitor such as crizotinib

Sample Required?

A sample of tumor tissue

Test Preparation Needed?

None