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Ammonia

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Also known as: NH3
Formal name: Ammonia, plasma

Board approvedAll content on Lab Tests Online has been reviewed and approved by our Editorial Review Board.

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

Chawla, J. (2015 Nov 30). Hyperammonemia. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/1174503-overview. Accessed February 2016.

De Biase, Irene et. al. (2016 Jan Updated). Mitochondrial Diseases. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/MitochondrialDz.html?client_ID=LTD. Accessed February 2016.

Haldeman-Englert, C. (2014 February 3, Updated). Hereditary urea cycle abnormality. MedlinePlus Medical Encyclopedia [On-line information]. Available online at https://www.nlm.nih.gov/medlineplus/ency/article/000372.htm. Accessed February 2016.

(2014 November 6 Updated). Roth, K. Genetics of Hyperammonemia. [On-line information]. Available online at http://emedicine.medscape.com/article/944996-overview. Accessed February 2016.

Devaraj, S. (2013 October 21, Updated). Ammonia. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2054408-overview. Accessed February 2016.

Dugdale, D. (2015 February 8 Updated). Ammonia – blood. MedlinePlus Medical Encyclopedia [On-line information]. Available online at https://www.nlm.nih.gov/medlineplus/ency/article/003506.htm. Accessed February 2016.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 22nd ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2011, Pg 299.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE, eds. 4th edition, St. Louis: Elsevier Saunders; 2006, Pp 1789-1791.

(August 12, 2014) Mayo Clinic. Reye's Syndrome. Available online at http://www.mayoclinic.org/diseases-conditions/reyes-syndrome/basics/definition/con-20020083. Accessed Feb 2016.

Sources Used in Previous Reviews

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference. 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 52-53.

Clarke, W. and Dufour, D. R., Editors (2006). Contemporary Practice in Clinical Chemistry. AACC Press, Washington, DC. Pp 270.

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests. Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 98-99.

Lehrer, J. (2006 October 13). Hepatic encephalopathy. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000302.htm. Accessed on 2/17/08.

(2006 September, Updated). Recommended Newborn Screening Tests: 29 Disorders. March of Dimes [On-line information]. Available online through http://www.marchofdimes.com. Accessed on 12/17/08.

Alerif, L. (2008 January 22, Updated). Hereditary urea cycle abnormality. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000372.htm. Accessed on 2/17/08.

Van Voorhees, B. (2006 August 18). Reye syndrome. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/001565.htm. Accessed on 2/17/08.

Hepatocerebral degeneration. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/001393.htm. Accessed on 2/17/08.

(© 2005). What is a Urea Cycle Disorder? National Urea Cycle Disorders Foundation [On-line information]. Available online through http://www.nucdf.org/ucd.htm. Accessed on 2/17/08.

KidsHealth, Nemours Foundation. Infections: Reye Syndrome (online information). Available online through http://kidshealth.org. Accessed March 2008.

S. Bakerman (2002). Bakerman's ABCs of Interpretive Laboratory Data (4th ed), Interpretive Laboratory Data, Scottsdale, AZ, Pp. 44-45.

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

(© 2004) Ammonia. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_al50.jsp.

(2004, May 24, Updated). Medical Management Guidelines (MMGs) for Ammonia (NH3). Agency for Toxic Substances and Disease Registry [On-line information]. Available online through http://www.atsdr.cdc.gov.

Miller, K. (2003 October 1). Do Ammonia Levels Correlate with Hepatic Encephalopathy? American Family Physician, Tips from Other Journals [On-line journal]. Available online through http://www.aafp.org.

Johnston, D. (1999 April 15). Special Considerations in Interpreting Liver Function Tests. American Family Physician [On-line journal]. Available online through http://www.aafp.org.

(© 1995-2004). Portal-Systemic Encephalopathy (Hepatic Encephalopathy; Hepatic Coma). The Merck Manual of Diagnosis and Therapy, Section 4. Hepatic And Biliary Disorders, Chapter 38. Clinical Features Of Liver Disease [On-line information]. Available online through http://www.merck.com.

(© 1995-2004). Liver Encephalopathy. The Merck Manual Second Home Edition, Section 10. Liver and Gallbladder Disorders, Chapter 135. Clinical Manifestations of Liver Disease [On-line information]. Available online through http://www.merck.com.

(© 1998-2003). Understanding the Basics, What is a Urea Cycle Disorder? National Urea Cycle Disorders Foundation [On-line information]. Available online through http://www.nucdf.org.

Burnett, R. (2002 September). September 2002 Q & A. College of American Pathologists [On-line information]. Available online through http://www.cap.org.

Mayo Clinic staff (2004 February 18). Reye's syndrome. MayoClinic.com [On-line information]. Available online through http://www.mayoclinic.com.

National Academy of Clinical Biochemistry. Laboratory Guidelines for Screening, Diagnosis and Monitoring of Hepatic Injury (2000). Available online through http://www.nacb.org.

Pagana K, Pagana T. Mosby's Manual of Diagnostic and Laboratory Tests. 4th edition. Pp 58-60.

ARUP Lab Tests. Ammonia, Plasma. Available online at http://www.aruplab.com/guides/ug/tests/0020043.jsp. Accessed October 2011.

MedlinePlus Medical Encyclopedia. Essential hypertension. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000153.htm. Accessed October 2011.

MedlinePlus Medical Encyclopedia. Malignant hypertension. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000491.htm. Accessed October 2011.

Elgouhari, HM. Q: What is the utility of measuring the serum ammonia level in patients with altered mental status? Cleveland Clinic Journal of Medicine. Available online at http://www.ccjm.org/content/76/4/252.full. Accessed October 2011.