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Antimitochondrial Antibody and AMA M2

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Also known as: Mitochondrial Antibody
Formal name: Antimitochondrial Antibody and Antimitochondrial M2 Antibody

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

Pyrsopoulos, N. and Reddy, K. (2016 June 3 Updated). Primary Biliary Cholangitis (Primary Biliary Cirrhosis). Medscape Drugs and Diseases. Available online at http://emedicine.medscape.com/article/171117-overview. Accessed on 02/18/17.

Lal, S. (2016 May 11 Updated). Primary biliary cirrhosis. MedlinePlus Medical Encyclopedia. Available online at https://medlineplus.gov/ency/article/000282.htm. Accessed on 02/18/17.

(2016 December 6, Updated). Primary Biliary Cholangitis (PBC, previously Primary Biliary Cirrhosis). American Liver Foundation. Available online at http://www.liverfoundation.org/abouttheliver/info/pbc/. Accessed on 02/18/17.

Tebo, A. (2016 November Updated). Primary Biliary Cirrhosis – PBC. ARUP Consult. Available online at https://arupconsult.com/content/primary-biliary-cirrhosis. Accessed on 02/18/17.

Shin, Y. (2014 December 5, Updated). Antimitochondrial Antibody. Medscape Laboratory Medicine. Available online at http://emedicine.medscape.com/article/2086548-overview Accessed on 02/18/17.

(2014 April Updated). Primary Biliary Cirrhosis. National Institute of Diabetes and Digestive and Kidney Diseases Available online at https://www.niddk.nih.gov/health-information/liver-disease/primary-biliary-cirrhosis. Accessed on 02/18/17.

(© 1995–2017). Mitochondrial Antibodies (M2), Serum. Mayo Clinic Mayo Medical Laboratories. Available online at http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8176. Accessed on 02/18/17.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO. Pp 82-83.

Lindor, K. (© 2002-2003) What is Primary Biliary Cirrhosis (PBC)? American Liver Foundation [On-line information]. Available online at http://www.liverfoundation.org/db/articles/1014.

(© 1995-2005). Primary Biliary Cirrhosis. The Merck Manual of Medical Information – Second Home Edition [On-line information]. Available online at http://www.merck.com/mmhe/print/sec10/ch136/ch136d.html.

(© 1995-2005). Primary Sclerosing Cholangitis. The Merck Manual of Medical Information – Second Home Edition [On-line information]. Available online at http://www.merck.com/mmhe/sec10/ch136/ch136e.html.

(© 2005). Mitochondrial M2 Antibody, IgG (ELISA). ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_a89b.jsp#1142095.

Beuers, U. and Rust, C. (2005 October 27). Overlap Syndromes. Medscape, from Semin Liver Dis. 2005; 25(3): 311-320. [On-line information]. Available online at http://www.medscape.com/viewarticle/512463.

Stone, C. (2004 November 10, Updated). Autoimmune liver disease panel. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003328.htm.

Stone, C. (2004 May 14). Primary biliary cirrhosis. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000282.htm.

Peng, S. (2005 April 20). Antimitochondrial antibody. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003529.htm.

(© 2003). Mitochondrial (M2) Antibody. LabCorp [On-line test information]. Available online at http://www.labcorp.com/datasets/labcorp/html/chapter/mono/se000750.htm.

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 85-86.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 272.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition: Saunders Elsevier, St. Louis, MO. Pp 746.

Dugdale, D. (Updated 2008 November 2). Autoimmune liver disease panel. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003328.htm. Accessed 1/29/09.

Christopher-Stine, L. (Updated 2006 August 22). Systemic lupus erythematosus. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000435.htm. Accessed 1/29/09.

Lehrer, J (2006 July 25 Updated). Autoimmune hepatitis. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000245.htm. Accessed 1/29/09.

Stone, C. (2008 May 20, Updated). Primary biliary cirrhosis. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000282.htm. Accessed 1/29/09.

Hill, H. (Updated 2008 September). Primary Biliary Cirrhosis. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/AutoimmuneDz/PBC.html#. Accessed 1/29/09.

Bylund DJ, Nakamura RM. Organ-specific autoimmune diseases. Henry’s Clinical Diagnosis and Laboratory Management, 21st ed., 2007. Pp 945-960.

(Updated 2012 September 26). Antimitochondrial Antibody. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2086548-overview#showall. Accessed February 2013.

Tebo, A. (Updated 2012 August). Primary Biliary Cirrhosis – PBC. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/PBC.html?client_ID=LTD#tabs=0. Accessed February 2013.

(© 1995–2013). Mitochondrial Antibodies (M2), Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/8176. Accessed February 2013.

Makover, M. (Updeate 2011 February 10). Antimitochondrial antibody. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003529.htm. Accessed February 2013.

Pyrsopoulos, N. and Reddy, K. (Updated 2012 January 4). Primary Biliary Cirrhosis. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/171117-overview. Accessed February 2013.

Dugdale, D. (Updated 2012 May 1). Primary biliary cirrhosis. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000282.htm. Accessed February 2013.

Shaffer, E. (Reviewed 2009 June) Laboratory Tests of the Liver and Gallbladder. Merck Manual for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed February 2013.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 87-88.

McPherson, R. and Pincus, M. (© 2011). Henry's Clinical Diagnosis and Management by Laboratory Methods 22nd Edition: Elsevier Saunders, Philadelphia, PA. Pp 304.

Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL eds, (2005). Harrison's Principles of Internal Medicine, 16th Edition, McGraw Hill, Pp 1860-1861.

(April 30, 2012) National Digestive Diseases Information Clearinghouse. Primary Biliary Cirrhosis. Available online at http://digestive.niddk.nih.gov/ddiseases/pubs/primarybiliarycirrhosis/index.aspx. Accessed May 2013.