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Antithrombin

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Also known as: Functional Antithrombin III; AT III; AT 3
Formal name: Antithrombin (Activity and Antigen)

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Dugdale, D. (Updated 2012 June 5). Antithrombin III. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003661.htm. Accessed September 2012.

Dugdale, D. (Updated 2011 February 28). Congenital antithrombin III deficiency. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000558.htm. Accessed September 2012.

Harper, J. (Updated 2011 August 1). Antithrombin III Deficiency. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/954688-overview through http://emedicine.medscape.com. Accessed September 2012.

Hart, K. et. al. (Updated 2011 November). Hypercoagulable States – Thrombophilia. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/Thrombophilia.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed September 2011.

(© 1995–2012). Unit Code 9030: Antithrombin Activity, Plasma. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/9030 through http://www.mayomedicallaboratories.com. Accessed September 2012.

(© 1995–2012). Unit Code 9031: Antithrombin Antigen, Plasma. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/9031 through http://www.mayomedicallaboratories.com. Accessed September 2012.

Lusky, K. (2010 September). In coagulation, reflexive testing algorithms do the trick. CAP Today [On-line information]. Available online through http://www.cap.org. Accessed September 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 105-107.

(January 10, 2012) Rajun A, et. al. Antithrombin Deficiency. Medscape Reference. Available online at http://emedicine.medscape.com/article/198573-overview through http://emedicine.medscape.com/. Accessed September 2012.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Antithrombin III pp. 100-101. Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Brose, M. (2003 June 1, Updated). Antithrombin III. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003661.htm.

Cohen, E. (2003 October 28, Updated). Congenital antithrombin III deficiency. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000558.htm.

(2002 November 19, Updated). Antithrombin. Massachusetts General Hospital, Pathology Service Laboratory Medicine Coag Test Handbook [On-line information]. Available online at http://www.mgh.harvard.edu/labmed/lab/coag/handbook/CO000300.htm through http://www.mgh.harvard.edu.

(2003 September, Modified). Antithrombin III Functional Assay and Antigen. Duke University Medical Center, Clinical Coagulation Laboratory, Coagulation Test Descriptions [On-line information]. Available online at http://pathology.mc.duke.edu/coag/TestDes.htm through http://pathology.mc.duke.edu.

(2003 Spring). Current approaches to the work-up of hypercoagulability: Antithrombin deficiency. College of American Pathologists, Newspath V 17 (2). Available online at http://www.cap.org/apps/docs/newspath/spring_2003/clinical.html through http://www.cap.org.

(© 2004) Antithrombin, Antigen. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_al65.jsp#3952516 through http://www.arup-lab.com.

Rodgers, G. et. al. (© 2004) Hemostasis/Thrombosis, General Information. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_fro8.jsp#1238723 through http://www.arup-lab.com.

(© 2004). Antithrombin, Enzymatic (Activity). ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_al66.jsp#3952541 through http://www.arup-lab.com.

(2001 June 26, Updated). Antithrombin Deficiency. University of Illinois - Urbana/Champaign, Carle Cancer Center, Hematology Resource Page, Patient Resources [On-line information]. Available online at http://www-admin.med.uiuc.edu/hematology/PtAntithrombin.htm through http://www-admin.med.uiuc.edu. 

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007).  Mosby's Diagnostic and Laboratory Test Reference 8th Edition:  Mosby, Inc., Saint Louis, MO. Pp 104-105.

Clarke, W. and Dufour, D. R., Editors (2006).  Contemporary Practice in Clinical Chemistry, AACC Press, Washington, DC.  Pp 231.

Wu, A. (2006).  Tietz Clinical Guide to Laboratory Tests, Fourth Edition.  Saunders Elsevier, St. Louis, Missouri. Pp 138-139.

Levin, M. (2007 March 9, Updated). Antithrombin III. MedlinePlus Medical Encyclopedia. Available online through http://www.nlm.nih.gov/medlineplus. Accessed on 3/9/08.

Nanda, R. (2007 April 27). Deep venous thrombosis. MedlinePlus Medical Encyclopedia. Available online through http://www.nlm.nih.gov/medlineplus. Accessed on 3/9/08.

Harper, J. (2007 August 16). Antithrombin III Deficiency. eMedicine. Available online through http://www.emedicine.com. Accessed on 3/9/08.