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Blood Ketones

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Also known as: Serum Ketone; Plasma Ketone; Beta-hydroxybutyrate; Ketone Bodies; Beta-hydroxybutyric Acid; Acetoacetate; Acetoacetic Acid; Acetone
Formal name: Blood Ketones
Related tests: Urine ketones (see Urinalysis - The Chemical Exam); Blood Gases; Glucose

Were you looking for urine ketones? Urine ketone testing is more common than blood ketone testing and may be performed as part of a urinalysis.

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Vorvick, L. (Updated 2011 February 1). Serum ketones test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003498.htm. Accessed December 2012.

Devkota, B. (Updated 2012 October 11). Ketone (Acetone). Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2087982-overview through http://emedicine.medscape.com. Accessed December 2012.

Raghavan, V. et. al. (Updated 2012 January 3). Diabetic Ketoacidosis. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/118361-overview through http://emedicine.medscape.com. Accessed December 2012.

Clarke, W., Editor (© 2011). Contemporary Practice in Clinical Chemistry 2nd Edition: AACC Press, Washington, DC. Pp 404.

McPherson, R. and Pincus, M. (© 2011). Henry's Clinical Diagnosis and Management by Laboratory Methods 22nd Edition: Elsevier Saunders, Philadelphia, PA. Pg 218.

Sources Used in Previous Reviews

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 972-973.

Hurd, R. (Updated 2007 October 31). Serum ketones. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003498.htm. Accessed February 2009.

Holt, E. (Updated 2008 June 17). Diabetic Ketoacidosis MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000320.htm. Accessed February 2009.

Mayo Clinic Staff (2008 February 9). Diabetic ketoacidosis. MayoClinic.com [On-line information]. Available online at http://www.mayoclinic.com/print/diabetic-ketoacidosis/DS00674/DSECTION=all&METHOD=print through http://www.mayoclinic.com. Accessed February 2009.

Hamdy, O. (Updated 2008 July 14). Diabetic Ketoacidosis eMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/118361-overview through http://emedicine.medscape.com. Accessed February 2009.

Trachtenbarg, D. (2005 May 1). Diabetic Ketoacidosis. American Family Physician [On-line information]. Available online at http://www.aafp.org/afp/20050501/1705.html through http://www.aafp.org. Accessed February 2009.

Sheikh-Ali, M. et. al. (2008 January). Can Serum _-Hydroxybutyrate Be Used to Diagnose Diabetic Ketoacidosis? Diabetes Care 31:643-647, 2008 [On-line information]. Available online at http://care.diabetesjournals.org/cgi/content/full/31/4/643 through http://care.diabetesjournals.org. Accessed February 2009.

Rose, K. and Collins, K. (2008 December 1). Vitreous Postmortem Chemical Analysis. CAP NewsPath [On-line information]. Available online through http://www.cap.org. Accessed February 2009.

(Updated 2008 December 30). Siezures and Epilepsy, Hope Through Research. NINDS [On-line information]. Available online at http://www.ninds.nih.gov/disorders/epilepsy/detail_epilepsy.htm through http://www.ninds.nih.gov. Accessed February 2009.

Rho, J. (Updated 2009 February 19). The Ketogenic Diet in Pediatric Epilepsy. The Charlie Foundation [On-line information]. Available online at http://www.charliefoundation.org/frames/diet/overview.php through http://www.charliefoundation.org. Accessed February 2009.

(2006 July). Answering your questions, Serum acetone testing. [On-line information]. PDF available for download at http://www.mlo-online.com/articles/0706/0706tips%20.pdf through http://www.mlo-online.com. Accessed February 2009.

(Modified 2008 August 11). Ketone Testing. Children’s Physician Network [On-line information]. Available online at http://www.cpnonline.org/CRS/CRS/pa_ketone_pep.htm through http://www.cpnonline.org. Accessed February 2009.

Wallace, T. and Matthews, D. (2004). Recent advances in the monitoring and management of diabetic ketoacidosis. QJM 2004 97(12):773-780. Available online at http://qjmed.oxfordjournals.org/cgi/content/full/97/12/773 through http://qjmed.oxfordjournals.org. Accessed February 2009.