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Calcitonin

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Also known as: Human Calcitonin; Thyrocalcitonin
Formal name: Calcitonin
Related tests: RET Oncogene; Calcium, TSH, Free T3 and Total T3, Free T4, Thyroglobulin, CEA

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

January 2016 review performed by Irene Shu, PhD, DABCC, Assistant Laboratory Director, USDTL.

Kaplan, Lawrence A. and Pesce, Amadeo J. (©2010). Clinical Chemistry: Theory, Analysis, Correlation, 5th Edition: Mosby, Inc. p 626.

Mayo Clinic Interpretive Handbook. Test 9160: Calcitonin, Serum, Clinical Information. Available online at http://www.mayomedicallaboratories.com/interpretive-guide/?alpha=C&unit_code=9160. Accessed November 2015.

Revised American Thyroid Association Guidelines for the Management of Medullary Thyroid Carcinoma. Thyroid, 25, 2015.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Brown, T., Updated (2004 January 27). Calcitonin. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003699.htm.

Cohen, E. Updated (2003 May 2). Medical Encyclopedia: Medullary carcinoma of thyroid. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000374.htm.

Burman, K. (2003 July 23). Topics in Thyroid Disease, Should All Patients With a Thyroid Nodule Have Routine Serum Calcitonin Measurements? Medcape, from Medscape Diabetes & Endocrinology 5(2) 2003 [On-line information]. Availableonline at http://www.medscape.com/viewarticle/458789?src=search.

Randolph, G. and Maniar, D. (2000). Medullary Carcinoma of the Thyroid. Medscape, from Cancer Control: Journal of the Moffitt Cancer Center [On-line information]. Available online at http://www.medscape.com/viewarticle/408987?src=search.

(© 1995-2005). Thyroid Gland Disorders, Introduction. The Merck Manual of Medical Information – Second Home Edition [On-line information]. Available online at http://www.merck.com/mmhe/sec13/ch163/ch163a.html.

Liebert, M. (2003 June 6). Thyroid Tests for the Clinical Biochemist and Physician, Calcitonin (CT) and RET Proto-Oncogene Measurement. Medscape from Thyroid 13(1):68-74, 2003 [On-line information]. Available online at http://www.medscape.com/viewarticle/452670?src=search.

Dumont, J.E., et. al. (2002 August 1, Revised). Chapter 1, The Phylogeny, Ontogeny, Anatomy, and Metabolic Regulation of the Thyroid, The Secretory Unit – The Follicle. Thyroid Disease Manager [On-line information]. Available online at http://www.thyroidmanager.org/Chapter1/1-frame.htm.

Wiesner, G. and Snow-Bailey, K. (2005 March 7, Updated). Multiple Endocrine Neoplasia Type 2. GeneReviews [On-line information]. Available online through http://www.genetests.org.

(© 2005). Calcitonin. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_a135.jsp#1059013.

Elisei, R; Bottici, V; Luchetti, F; Di Coscio, G; Romei, C; Grasso, L; Miccoli, P; Iacconi, P; Basolo, F; Pinchera, A; Pacini, F: Impact of Routine Measurement of Serum Calcitonin on the Diagnosis and Outcome of Medullary Thyroid Cancer: Experience in 10,864 Patients with Nodular Thyroid Disorders. J Clin Endocrinol Metab 2004;89:163-168.

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 220-221.

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 194-199.

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition]. Pp 285.

Schlumberger, M. et. al. (2007 December 10). New Therapeutic Approaches to Treat Medullary Thyroid Carcinoma. Medscape from Nat Clin Pract Endocrinol Metab 4(1):22-32, 2007. [On-line information]. Available online at http://www.medscape.com/viewarticle/566894. Accessed on 11/1/08.

Hershman, J. (2008 June, Revised). Thyroid Cancers. Merck Manual for Healthcare Professionals [On-line information]. Available online at http://www.merck.com/mmpe/sec12/ch152/ch152j.html?qt=calcitonin&alt=sh. Accessed on 11/1/08.

Lyon, E. et. al. (2008 May, Reviewed) Multiple Endocrine Neoplasias - MEN. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/EndocrineDz/MEN.html#. Accessed on 11/1/08.

Wiesner, G. and Snow-Bailey, K. (2005 March 7, Update). Multiple Endocrine Neoplasia Type 2. GeneReviews [On-line information]. Available online at http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene&part=men2. Accessed on 11/1/08.

(Updated October 3, 2007) American Cancer Society: How is Thyroid Cancer Diagnosed? Available online at http://www.cancer.org/docroot/CRI/content/CRI_2_4_3X_How_is_thyroid_cancer_diagnosed_43.asp?sitearea=. Accessed November 2008.

(Update December 6, 2007) Rennert N. Calcitonin. MedlinePlus Medical Encyclopedia. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003699.htm. Accessed November 2008.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007, Pp 341-342.

(© 1995-2012). Test ID: CATN9160 Calcitonin, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/9160. Accessed January 2012.

Meikle, A. W. (Updated 2011 October). Thyroid Cancer. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/ThyroidCancer.html?client_ID=LTD#tabs=0. Accessed January 2012.

(Revised 2011 June 29). Thyroid Cancer, How is thyroid cancer diagnosed? American Cancer Society [On-line information]. Available online at http://www.cancer.org/Cancer/ThyroidCancer/DetailedGuide/thyroid-cancer-diagnosis. Accessed January 2012.

Dugdale, D. (Updated 2010 March 2). Medullary carcinoma of thyroid. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000374.htm. Accessed January 2012.

Konstantakos, A. (Updated 2011 August 12). Medullary Thyroid Carcinoma. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/282084-overview. Accessed January 2012.

Richards, M. et. al. (2010 February 19). Multiple Endocrine Neoplasia, Type 2. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/123447-overview. Accessed January 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 212-213.