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Cholesterol

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Also known as: Blood Cholesterol
Formal name: Total Cholesterol

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Sep 2002. PDF available for download at http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3full.pdf through http://www.nhlbi.nih.gov. Accessed July 21, 2013.

(©2012) American Heart Association. Cholesterol Levels. Available online at http://www.heart.org/HEARTORG/Conditions/Cholesterol/Cholesterol_UCM_001089_SubHomePage.jsp through http://www.heart.org. Accessed July 21, 2013.

(November 2012) American Association of Family Physicians. High Cholesterol. Available online at http://familydoctor.org/familydoctor/en/diseases-conditions/high-cholesterol.html through http://familydoctor.org. Accessed July 19, 2013.

Kavey R-EW, et al. Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: Summary report. Pediatrics 2011; 128: DOI:10.1542/peds.2009-2107C. PDF available for download at http://pediatrics.aappublications.org/site/misc/2009-2107.pdf through http://pediatrics.aappublications.org. Accessed July 19, 2013.

KidsHealth.org. Cholesterol and Your Child. Available online at http://kidshealth.org/parent/medical/heart/cholesterol.html# through http://kidshealth.org. Accessed July 20, 2013.

Kathiresan, S. 2006. Increased Small Low-Density Lipoprotein Particle Number, A Prominent Feature of the Metabolic Syndrome in the Framingham Heart Study. Circulation. PDF available for download at http://circ.ahajournals.org/content/113/1/20.full.pdf through http://circ.ahajournals.org. Accessed July 20, 2013.

Blake G, et al. September 23, 2002. Low-Density Lipoprotein Particle Concentration and Size as Determined by Nuclear Magnetic Resonance Spectroscopy as Predictors of Cardiovascular Disease in Women. Circulation. Available online at http://circ.ahajournals.org/content/106/15/1930.full through http://circ.ahajournals.org. Accessed July 20, 2013.

Blakenstein R, et al. July 2011. Predictors of Coronary Heart Disease Events Among Asymptomatic Persons With Low Low-Density Lipoprotein Cholesterol. Journal of the American College of Cardiology Volume 58, Issue 4, Pp 364–374.

Krauss R. 2010 Aug;21. Lipoprotein subfractions and cardiovascular disease risk. Curr Opin Lipidol (4):305-11. Abstract available online at http://www.ncbi.nlm.nih.gov/pubmed/20531184 through http://www.ncbi.nlm.nih.gov. Accessed July 2013.

Prado K, et al. 2011 Sep-Oct. Low-density lipoprotein particle number predicts coronary artery calcification in asymptomatic adults at intermediate risk of cardiovascular disease. J Clin Lipidol (5):408-13. Abstract available online at http://www.ncbi.nlm.nih.gov/pubmed/21981843 through http://www.ncbi.nlm.nih.gov. Accessed July 2013.

Lavie C, et.al. May 2012. To B or Not to B: Is Non–High-Density Lipoprotein Cholesterol an Adequate Surrogate for Apolipoprotein B? Mayo Clin Proc. 2010 May; 85(5): 446–450. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861974/ through http://www.ncbi.nlm.nih.gov. Accessed July 2013.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

National Heart, Lung, and Blood Institute of the National Institutes of Health, United States Department of Health and Human Services. Third report of the National Cholesterol Education Program (NCEP) Expert Panel on detection, evaluation, and treatment of high blood pressure in adults (Adult Treatment Panel III). Bethesda, Md. 2001 May. Available online at http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3_rpt.htm

American Heart Association. How to Get Your Cholesterol Tested. (Updated April 4, 2008) Available online at http://americanheart.org/presenter.jhtml?identifier=541 through http://americanheart.org. Accessed July 2008.

Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). May 2001. PDF available for download at http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3full.pdf through http://www.nhlbi.nih.gov. Accessed July 2008.

American Academy of Family Physicians. Cholesterol: What Your Level Means. (Updated October 2007). Available online at http://familydoctor.org/online/famdocen/home/common/heartdisease/risk/029.html through http://familydoctor.org. Accessed July 2008.

Daniels, SR, Greer FR, and the Committee on Nutrition. Lipid screening and cardiovascular health in childhood (clinical report). Jul 2008. Pediatrics 122:198-208.

American Academy of Pediatrics. AAP issues new guidelines on cholesterol screening (press release). 7 Jul 2008. Available online at http://www.aap.org/new/july08lipidscreening.htm through http://www.aap.org. Accessed August 2008.

American Academy of Pediatrics Lipid Screening and Cardiovascular Health in Childhood. Pediatrics Vol. 122 No. 1 July 2008, pp. 198-208. Available online at http://aappolicy.aappublications.org/cgi/content/full/pediatrics;122/1/198 through http://aappolicy.aappublications.org. Accessed September 2008.