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Coagulation Factors

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Also known as: Factor Assays; Blood Clotting Factors; Clotting Factors [or by the individual factor number (Factor I, Factor II, etc.) or name (Fibrinogen, Prothrombin, etc.)]
Formal name: [see table]

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 272–278.

(© 1995-2012). Test ID: F8A Coagulation Factor VIII Activity Assay, Plasma. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9070 through http://www.mayomedicallaboratories.com. Accessed May 2012.

Dugdale, D. (2011 February 28). Factor VII assay. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003676.htm. Accessed May 2012.

Schwartz, R. et. al. (Updated 2011 February 2). Factor II. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/209742-overview#showall through http://emedicine.medscape.com. Accessed May 2012.

Ramanarayanan, J. et. al. (Updated 2011 May 19). Factor VII. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/209585-overview through http://emedicine.medscape.com. Accessed May 2012.

Devkota, B. (Updated 2012 April 16). Factor II, Prothrombin. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2085225-overview#showall through http://emedicine.medscape.com. Accessed May 2012.

Spence, R. et. al. (2010 January 12). Hemostatic Disorders, Nonplatelet. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/210467-overview through http://emedicine.medscape.com. Accessed May 2012.

Clarke, W., Editor (© 2011). Contemporary Practice in Clinical Chemistry 2nd Edition: AACC Press, Washington, DC. Pp 265-272.

Sources Used in Previous Reviews

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 275-280.

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Clarke, W. and Dufour, D. R., Editors (2006). Contemporary Practice in Clinical Chemistry, AACC Press, Washington, DC. Harris, N. et. al. Chapter 19: Assessment of Hemostasis in the Clinical Laboratory pp 227-239.

Moake, J. (2006 May, Revised). Blood Disorders, Bleeding and Clotting Disorders, Introduction. Merck Manual Home Edition [On-line information]. Available online through http://www.merck.com. Accessed on 3/14/07.

McPherson R, Pincus M, eds, (2007). Henry's Clinical Diagnosis and Management by Laboratory Methods, 21st edition, Saunders Elsevier.

Colman RW, Marder VJ, Clowes AW, George JN, Goldhaber SZ, eds, (2006). Hemostasis and Thrombosis, Basic Principles and Clinical Practice. 5th edition, Lippincott Williams and Wilkins.

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Van Cott, E. and Laposata, M (2002 November 19, Revised). Coagulation Factor Assays. Mass Gen Hosp Handbook [On-line information]. Available online through http://www.mgh.harvard.edu.

Vitamin K Deficiency. The Merck Manual of Diagnosis and Therapy, Section 1. Nutritional Disorders, Chapter 3. Vitamin Deficiency, Dependency, And Toxicity [On-line information]. Available online through http://www.merck.com.

(2003 March 25). Vitamin K. The Linus Pauling Institute's Micronutrient Information Center [On-line information]. Available online through http://lpi.oregonstate.edu.

DeLoughery, T. (1999 March 15). Tests of Hemostasis and Thrombosis. OHSU [Online student handout]. Available online through http://www.ohsu.edu.

Elstrom, R. (2001 October 21, Updated). Bleeding disorders. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/001304.htm.

Elstrom, R. (2001 November 10, Updated). Factor XII assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003681.htm.

Elstrom, R. (2001 October 14, Updated). Factor XII (Hageman factor) deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000545.htm.

Elstrom, R. (2001 October 14, Updated). Factor X deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000553.htm.

Elstrom, R. (2001 October 9, Updated). Factor VIII assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003678.htm.

Elstrom, R. (2001 November 10, Updated). Factor IX assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003679.htm.

Elstrom, R. (2001 November 10, Updated). Factor V assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003675.htm.

Elstrom, R. (2002 May 6, Updated). Factor V deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000550.htm.

Elstrom, R. (2001 October 6, Updated). Hemophilia B. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000539.htm.

Elstrom, R. (2001 November 10, Updated). Factor II deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000549.htm.

Elstrom, R. (2001 November 10, Updated). Factor II assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003674.htm.

Elstrom, R. (2001 November 10, Updated). Factor X assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003680.htm.

Elstrom, R. (2001 November 25, Updated). PT. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003652.htm.

Elstrom, R. (2001 November 25, Updated). PTT. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003653.htm.

Elstrom, R. (2001 November 10, Updated). Factor VII assay. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003676.htm.

Elstrom, R. (2001 October 14, Updated). Factor VII deficiency. MEDLINEplus Health Information, Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000548.htm.

What is a Bleeding Disorder?, History. National Hemophilia Foundation, Bleeding Disorders Info Center [On-line information]. Available online through http://www.hemophilia.org.

What is a Bleeding Disorder? National Hemophilia Foundation, Bleeding Disorders Info Center [On-line information]. Available online through http://www.hemophilia.org.

Hemophilia A (Factor VIII Deficiency). National Hemophilia Foundation, Bleeding Disorders Info Center [On-line information]. Available online through http://www.hemophilia.org.

Menta, S. (1999 Spring). The Coagulation Cascade. Physiology Disorders Evaluation, College of Medicine, University of Florida [On-line information]. Available online through http://www.medinfo.ufl.edu.