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Cortisol

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Also known as: Urinary Cortisol; Salivary Cortisol; Free Cortisol; Dexamethasone Suppression Test; DST; ACTH Stimulation Test
Formal name: Cortisol

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Griffing, G. (Updated 2014 March 11). Serum Cortisol. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2088826-overview through http://emedicine.medscape.com. Accessed February 2015.

Straseski, J. (Updated 2015 January). Adrenal Hyperfunction - Cushing Syndrome. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/CushingSyndrome.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed February 2015.

Wisse, B. (Updated 2013 November 7). Cortisol blood test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003693.htm through http://www.nlm.nih.gov. Accessed February 2015.

(© 1995–2015). Cortisol, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/8545 through http://www.mayomedicallaboratories.com. Accessed February 2015.

Straseski, J. (Updated 2014 November). Adrenal Insufficiency. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/AdrenalInsufficiency.html?client_ID=LTD through http://www.arupconsult.com. Accessed February 2015.

Morley, J. (Revised 2013 February). Overview of the Endocrine System. The Merck Manual Professional Edition [On-line information]. Available online through http://www.merckmanuals.com. Accessed February 2015.

Pagana, K. D., Pagana, T. J., and Pagana, T. N. (© 2015). Mosby's Diagnostic & Laboratory Test Reference 12th Edition: Mosby, Inc., Saint Louis, MO. Pp 301-303.

Sources Used in Previous Reviews

MayoClinic.com. Cushings Syndrome (online information). Available online through http://www.mayoclinic.com. Accessed March 2008.

Restituto P, et.al. Advantage of salivary cortisol measurements in the diagnosis of glucocorticoid related disorders. Clin Biochem. 2008 Feb 5 [Epub ahead of print]. Available online through http://www.ncbi.nlm.nih.gov/pubmed. Accessed March 2008.

De Castro M, Moreira A. Screening and Diagnosis of Cushings Syndrome. Arq Bras Endocrinol Metab 2007;51/8.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007.

Pituitary Network Association. Adrenal Insufficiency (Secondary Addison's or Addison's Disease). Available online through  http://www.pituitary.org/. Accessed March 2008.

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Jain, T. (2004 February 2, Updated). Cortisol level. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003693.htm.

(2002 June). Cushing's syndrome. NIDDK, NIH Publication No. 02-3007 [On-line information]. Available online through http://www.niddk.nih.gov.

(© 2005). Cortisol, Serum or Plasma. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online through http://www.arup-lab.com.

(© 1995-2004). Cushing's Syndrome. The Merck Manual Second Home Edition [On-line information]. Available online through http://www.merck.com.

Raff, H. and Findling, J. (2003). A Physiologic Approach to Diagnosis of the Cushing Syndrome. Ann Intern Med. 2003;138:980-991 [on-line journal]. Available online through http://www.annals.org.

Pagana K, Pagana T. (2006). Mosby's Manual of Diagnostic and Laboratory Tests. 3rd edition. St. Louis: Mosby Elsevier.

(© 1995-2011). Unit Code 8545: Cortisol, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/8545 through http://www.mayomedicallaboratories.com. Accessed September 2011.

Meikle, W. and Roberts, W. (Updated 2011 January). Adrenal Insufficiency. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/AdrenalInsufficiency.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed September 2011.

Adler, G. (Updated 2011 July 25). Cushing Syndrome. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/117365-overview through http://emedicine.medscape.com. Accessed September 2011.

(2009 May). Adrenal Insufficiency and Addison's Disease. National Endocrine and Metabolic Diseases Information Service [On-line information]. Available online at http://endocrine.niddk.nih.gov/pubs/addison/addison.aspx through http://endocrine.niddk.nih.gov. Accessed September 2011.

Eckman, A. (2009 November 23). Cortisol. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003693.htm. Accessed September 2011.

Eckman, A. (2009 November 23). Cortisol-urine. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003703.htm. Accessed September 2011.

Meikle, A. W. and Roberts, W. (Updated 2011 January). Adrenal Hyperfunction - Cushing Syndrome. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/CushingSyndrome.html through http://www.arupconsult.com. Accessed September 2011.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 311-313.