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Creatinine Clearance

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Also known as: Creatinine Clearance, Urine; CRCL; CCT
Formal name: Creatinine Clearance

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

(December 2014). Horowitz, G. Creatinine. Medscape. Available online at http://emedicine.medscape.com/article/2054342-overview. Accessed January 2017.

(2013) National Kidney Foundation. Calculating Kidney Function. Available online at https://www.kidney.org/atoz/content/kidneytests. Accessed January 2017.

(June 2013) E. Sandilands, et al. Measurement of renal function in patients with chronic kidney disease. British Journal of Clinical Pharmacology. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791974/. Accessed January 2017.

(August 2015). U.S. National Library of Medicine. Creatinine Clearance. MedlinePlus. Available online at https://medlineplus.gov/ency/article/003611.htm. January 2017.

Sources Used in Previous Reviews

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Clinical Chemistry: Principles, Procedures, Correlations. Michael L. Bishop, Janet L. Duben-Engelkirk, Edward P. Fody. Lipincott Williams & Wilkins, 4th Edition.

Mitchell G. Scott, PhD. Division of Laboratory Medicine, Washington University School of Medicine, St. Louis, MO.

Martin H. Kroll, MD. Director of Clinical Chemistry, VA Medical Center, Dallas, TX.

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Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

(2002 March). Medical Tests of Kidney Function. National Kidney and Urologic Diseases Information Clearinghouse, NIH Publication No. 02; 4623 [On-line information]. Available online at http://kidney.niddk.nih.gov/kudiseases/pubs/kidneytests/index.htm.

Esson, M. and Schrier, R. (2002). Diagnosis and Treatment of Acute Tubular Necrosis. Ann Intern Med 2002;137:744-752 [On-line journal]. PDF available for download at http://www.annals.org/cgi/reprint/137/9/744.pdf.

Agha, Irfan (2004 February 11, Updated). Creatinine - serum. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003475.htm.

Agha, Irfan (2004 February 11, Updated). Creatinine - urine. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003610.htm.

Agha, Irfan (2004 February 11, Updated). Creatinine clearance. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003611.htm.

Agha, Irfan (2003 August 7, Updated). BUN. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003474.htm.

Agrawal, M. and Swartz, R. (2000 April 1). Acute Renal Failure. American Family Physician [On-line journal]. Available online at http://www.aafp.org/afp/20000401/2077.html.

Nissl, J. (2004 September 20, Updated). Creatinine and Creatinine Clearance WebMD [On-line information]. Available online at http://my.webmd.com/hw/kidney_failure/hw4322.asp.

Pagana K, Pagana T. Mosby's Manual of Diagnostic and Laboratory Tests. 3rd Edition, St. Louis: Mosby Elsevier; 2006, Pp 209-211.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER and Bruns DE, eds. 4th ed. St. Louis, Missouri: Elsevier Saunders; 2006, Pp 797-798; 818-819.

Clarke, W. and Dufour, D. R., Editors (2006). Contemporary Practice in Clinical Chemistry, AACC Press, Washington, DC, Pg 43.

(February 2009) National Kidney and Urologic Diseases Information Clearinghouse. The Kidneys and How they Work. Available online at http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/index.htm#tests. Accessed September 2009.

(Updated September 4, 2007) Silberberg, C. MedlinePlus Medical Encyclopedia: Creatinine Clearance. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003611.htm. Accessed September 2009.

Dugdale, D. (Updated 2011 August 21). Creatinine clearance. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003611.htm. Accessed November 2012.

Medscape Editorial Staff (Updated 2012 October 1). Creatinine Clearance. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2117892-overview. Accessed November 2012.

(© 1995-2012). Creatinine Clearance. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/8500. Accessed November 2012.

Wilhelm, S. and Kale-Pradhan, P. (2011 July 29). Estimating Creatinine Clearance. Medscape News Today from Pharmacotherapy. 2011;31(7):658-664 [On-line information]. Available online at http://www.medscape.com/viewarticle/746232. Accessed November 2012.

Arora, P. (Updated 2012 March 28). Chronic Kidney Disease. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/238798-overview. Accessed November 2012.

(Updated 2012 March 23). The Kidneys and How They Work. National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC) [On-line information]. Available online at http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/. Accessed November 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 329-333.

Clarke, W., Editor (© 2011). Contemporary Practice in Clinical Chemistry 2nd Edition: AACC Press, Washington, DC. Pp 78-79.