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C-Reactive Protein

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Also known as: CRP
Formal name: C-Reactive Protein

Were you looking for the high-sensitivity CRP (hs-CRP) test, used to assess your risk of cardiovascular disease?

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Devkota, B. (Updated 2014 January 17). C-Reactive Protein. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2086909-overview through http://emedicine.medscape.com. Accessed February 2015.

Andreeva, E. and Melbye, H. (2014). Usefulness of C-reactive Protein Testing in Acute Cough/Respiratory Tract Infection An Open Cluster-Randomized Clinical Trial With C-Reactive Protein Testing in the Intervention Group. Medscape Multispecialty BMC Fam Pract. 2014;15(80) [On-line information]. Available online at http://www.medscape.com/viewarticle/826213 through http://www.medscape.com. Accessed February 2015.

Boggs, W. (2014 November 13). C-reactive Protein as Biomarker Might Reduce Antibiotic Use. Medscape Multispecialty Reuters Health Information [On-line information]. Available online at http://www.medscape.com/viewarticle/834810 through http://www.medscape.com. Accessed February 2015.

Genzen, J. (Updated 2014 May). Acute Phase Proteins - Acute Phase Reactants. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/AcutePhaseReactants.html through http://www.arupconsult.com. Accessed February 2015.

Teitel, A. (Updated 2013 February 11). C-reactive protein. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003356.htm through http://www.nlm.nih.gov. Accessed February 2015.

Delves, P. (Revised 2014 November). Components of the Immune System. The Merck Manual Professional Edition [On-line information]. Available online through http://www.merckmanuals.com. Accessed February 2015.

Pagana, K. D., Pagana, T. J., and Pagana, T. N. (© 2015). Mosby's Diagnostic & Laboratory Test Reference 12th Edition: Mosby, Inc., Saint Louis, MO. Pp 306-307.

Sources Used in Previous Reviews
A Manual of Laboratory & Diagnostic Tests. 6th ed. Fischbach F, ed. Philadelphia: Lippincott Williams & Wilkins; 2000: 619-620.

MedlinePlus Medical Encyclopedia. C-reactive protein. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003356.htm.

Nader Rifai, PhD. Department of Laboratory Medicine, Children's Hospital, Boston, MA.

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 190-193.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007, Pp 224, 240.

Clarke, W. and Dufour, D. R., Editors (2006). Contemporary Practice in Clinical Chemistry, AACC Press, Washington, DC, Pg 203.

Makover, M. (Updated 2011 February 10). C-reactive protein. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003356.htm. Accessed October 2011.

(© 1995–2011). Unit Code 9731: C-Reactive Protein (CRP), Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/9731 through http://www.mayomedicallaboratories.com. Accessed October 2011.

Rollins, G. (2009 February). The JUPITER Trial and CRP, Will the Results Change Clinical Practice? Clinical Laboratory News v 35 (2) [On-line information]. Available online at http://www.aacc.org/publications/cln/2009/February/Pages/CovStory2Feb09.aspx through http://www.aacc.org. Accessed October 2011.

Ridker, P. (2009 February). C-Reactive Protein: Eighty Years from Discovery to Emergence as a Major Risk Marker for Cardiovascular Disease. Clinical Chemistry 55:2 209–215 (2009) [On-line information]. Available online at http://www.clinchem.org/cgi/reprint/55/2/209 through http://www.clinchem.org. Accessed October 2011.

Lowry, F. (2010 March 23). CRP Test Guides Antibiotic Prescribing for Respiratory Tract Infections. From Medscape Medical News [On-line information]. Available online at http://www.medscape.com/viewarticle/719005 through http://www.medscape.com. Accessed October 2011.

Lee, C. and Hammel, J. (Updated 2011 April 15). Temporal Arteritis in Emergency Medicine. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/809492-overview through http://emedicine.medscape.com. Accessed October 2011.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 319-321.