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Dengue Fever Testing

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Also known as: Dengue Fever Antibodies; Dengue Fever Virus
Formal name: Dengue Antibodies (IgG, IgM); Dengue Virus by PCR

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

(2016 July Updated). Dengue and severe dengue. World Health Organization Fact sheet. Available online at http://www.who.int/mediacentre/factsheets/fs117/en/. Accessed on 1/22/17.

Shepherd, S. and Hinfey, P. (2015 October 5 Updated). Dengue. Medscape Drugs and Diseases. Available online at http://emedicine.medscape.com/article/215840-overview#showall. Accessed on 1/22/17.

Couturier, M. and Hillyard, D. (2016 December Updated). Dengue Fever Virus. ARUP Consult. Available online at https://arupconsult.com/content/dengue-fever-virus. Accessed on 1/22/17.

(© 1995–2017). Dengue Virus Antibody/Antigen Panel, Serum. Mayo Clinic Mayo Medical Laboratories. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/62869. Accessed on 1/22/17.

Hata, D. J. (2014 June). Dengue Fever – An Update. Mayo Clinic Mayo Medical Laboratories Hot Topics. Available online at http://www.mayomedicallaboratories.com/articles/hot-topic/2014/06-01-dengue-fever/index.html. Accessed on 1/22/17.

(2013 April 12). CDC DENV-1-4 Real-Time RT-PCR Assay for Detection and Serotype Identification of Dengue Virus. CDC. Available online at https://www.cdc.gov/dengue/resources/rt-pcr/cdcpackageinsert.pdf. Accessed on 1/22/17.

(2016 January 20 Updated). Dengue Laboratory Guidance and Diagnostic Testing. CDC. Available online at https://www.cdc.gov/dengue/clinicallab/laboratory.html. Accessed on 1/22/17.

(February 7, 2016) Centers for Disease Control and Prevention, Division of Vector-Borne Diseases. Revised diagnostic testing for Zika, chikungunya, and dengue viruses in US Public Health Laboratories. Available online at https://www.cdc.gov/zika/pdfs/denvchikvzikv-testing-algorithm.pdf. Accessed March 2017.

Sources Used in Previous Reviews

De Paula, S. and Fonseca, B. (2004). Dengue: a review of the laboratory tests a clinician must know to achieve a correct diagnosis. The Brazilian Journal of Infectious Diseases: an Official Publication of the Brazilian Society of Infectious Diseases. Available online at http://europepmc.org/abstract/MED/15880229. Accessed June 2013.

Lima, M. et al. (2010). Comparison of three commercially available Dengue NS1 Antigen Capture Assays for acute diagnosis of Dengue in Brazil. PLoS Neglected Tropical Diseases. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897844/. Accessed 5/30/2013.

Rathakrishnan, A., Sekaran, S. (2013). New development in the diagnosis of dengue infections. Expert Opinion on Medical Diagnostics. Available online at http://www.ncbi.nlm.nih.gov/pubmed/23530846. Accessed 6/1/2013.

Sood, R. (© 2006). Textbook of Medical Laboratory Technology. Jaypee Brothers Publishers. New Dehli, India. Pp 780-787.

World Health Organization. (2009) Dengue Guidelines for Diagnosis, Treatment, Prevention and Control. PDF available for download at http://whqlibdoc.who.int/publications/2009/9789241547871_eng.pdf. Accessed 5/15/2013.

(October 5, 2010) Centers for Disease Control and Prevention. Dengue. Available online at http://www.cdc.gov/Dengue/. Accessed June 2013.

Cuzzubo A, et al. Use of Recombinant Envelope Proteins for Serological Diagnosis of Dengue Virus Infection in an Immunochromatographic Assay. Clin Vaccine Immunol November 2001 vol. 8 no. 6 1150-1155. Available online at http://cvi.asm.org/content/8/6/1150.full. Accessed June 2013.

(September 30, 2011) Mayo Clinic. Dengue Fever. Available online at http://www.mayoclinic.com/health/dengue-fever/DS01028. Accessed June 2013.

(January 23, 2013) National Institute of Allergy and Infectious Diseases. Dengue Fever. Available online at http://www.niaid.nih.gov/topics/denguefever/Pages/default.aspx. Accessed June 2013.

CDC. 2012 Yellow Book. Dengue Fever & Dengue Hemorrhagic Fever. Available online at http://wwwnc.cdc.gov/travel/yellowbook/2012/chapter-3-infectious-diseases-related-to-travel/dengue-fever-and-dengue-hemorrhagic-fever. Accessed July 2013.

Florida Department of Health. Dengue Fever. Available online at http://www.doh.state.fl.us/environment/medicine/arboviral/Dengue.html. Accessed July 2013.