Proceeds from website advertising help sustain Lab Tests Online. AACC is a not-for-profit organization and does not endorse non-AACC products and services.

Epstein-Barr Virus (EBV) Antibody Tests

Print this article
Share this page:
Also known as: EBV Antibodies; EBV VCA-IgM Ab; EBV VCA-IgG Ab; EBNA-IgG Ab; EA-D IgG Ab
Formal name: Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM, IgG; Epstein-Barr Virus Antibody to Nuclear Antigen, IgG; Epstein-Barr Virus Antibody to Early D Antigen, IgG; Heterophile Antibodies

Board approvedAll content on Lab Tests Online has been reviewed and approved by our Editorial Review Board.

Article Sources

« Return to Related Pages

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

(April 2011) Su-Mei Cao, et al. Fluctuations of Epstein-Barr Virus Serological Antibodies and Risk for Nasopharyngeal Carcinoma: A Prospective Screening Study with a 20-Year Follow-Up. PLOS One. Available online at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0019100. Accessed June 12, 2016.

(Jan 2014) Centers for Disease Control and Prevention. Epstein-Barr Virus and Infectious Mononucleosis. Available online at http://www.cdc.gov/epstein-barr/laboratory-testing.html. Accessed June 11, 2016.

(Oct 2015) Cunha, B.A., et al. Infectious Mononucleosis Workup. Medscape. Available online at http://emedicine.medscape.com/article/222040-workup. Accessed June 13, 2016.

(Aug 2004) Hess, R. Routine Epstein-Barr Virus Diagnostics from the Laboratory Perspective: Still Challenging after 35 Years. Journal of Clinical Microbiology. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC497621/. Accessed June 11, 2016.

(2015) Reshkova, V. et al. Evaluation of Antiviral Antibodies against Epstein-Barr Virus and Neurotransmitters in Patients with Fibromyalgia. Journal of Neurology and Neuroscience. Available online at http://www.jneuro.com/neurology-neuroscience/evaluation-of-antiviral-antibodies-against-epsteinbarr-virus-and-neurotransmitters-in-patients-with-fibromyalgia.php?aid=7360. Accessed June 11, 2016.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO. Pp 373-375.

Ebell, M. (2004 October 1). Epstein-Barr Virus Infectious Mononucleosis. American Family Physician [On-line journal]. Available online at http://www.aafp.org/afp/20041001/1279.html.

Levy, D. (2004 January 19, Updated). Epstein-Barr virus test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003513.htm.

(© 1995-2005). Epstein-Barr Virus Infection. The Merck Manual- Second Home Edition [On-line information]. Available online at http://www.merck.com/mmhe/sec17/ch198/ch198f.html.

(© 2005). Epstein-Barr Virus. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_a238.jsp#1147825.

Schmid, S., Leader Herpesvirus Group (2005 September 13, Updated). Epstein-Barr Virus and Infectious Mononucleosis. CDC, National Center for Infectious Diseases [On-line information]. Available online at http://www.cdc.gov/ncidod/diseases/ebv.htm.

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 401-403.

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 1556-1557.

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition]. Pp 663.

Smith, D. S. (2007 August 6). Epstein-Barr virus test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003513.htm. Accessed on 11/23/08.

Bennett, N. J. and Domachowske, J (2008 August 12). Mononucleosis and Epstein-Barr Virus Infection. eMedicine [On-line information]. Available online at http://www.emedicine.com/ped/TOPIC705.HTM. Accessed on 11/23/08.

(© 2006-2008). Epstein-Barr Virus – EBV. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/InfectiousDz/Viruses/EBV.html. Accessed on 11/23/08.

Mayo Clinic Staff (2008 June 28). Mononucleosis. MayoClinic [On-line information]. Available online at http://www.mayoclinic.com/health/mononucleosis/DS00352. Accessed on 11/23/08.

(2005 November). Infectious Mononucleosis. The Merck Manual for Healthcare Professionals [On-line information]. Available online at http://www.merck.com/mmpe/sec14/ch189/ch189f.html?qt=EBV&alt=sh. Accessed on 11/23/08.

Peridin F, et. al (Published online 2007 March 28). Comparison of commercial and in-house Real-time PCR assays for quantification of Epstein-Barr virus (EBV) DNA in plasma. BMC Microbiol. 2007; 7: 22. Available online at http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=pmc1852802. Accessed January 2009.

(Updated Feb 2, 2009) Centers for Disease Control and Prevention. Epstein-Barr Virus and Infectious Mononucleosis. Available online at http://www.cdc.gov/ncidod/diseases/ebv.htm. Accessed February 2009.

Bennett, N. and Domachowske, J. (Updated 2012 May 30). Pediatric Mononucleosis and Epstein-Barr Virus Infection. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/963894-overview. Accessed November 2012.

Vorvick, L. (Updated 2011 August 24). Epstein-Barr virus test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003513.htm. Accessed November 2012.

Delgado, J. et. al. (Updated 2012 August). Epstein-Barr Virus – EBV. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/EBV.html?client_ID=LTD. Accessed November 2012.

(© 1995-2012). Epstein-Barr Virus (EBV) Antibody Profile, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/84421. Accessed November 2012.

Cunha, B. and Levy, C. (Updated 2011 September 21). Infectious Mononucleosis. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/222040-overview. Accessed November 2012.

Mayo Clinic Staff (2010 June 26). Mononucleosis. Mayo Clinic [On-line information]. Available online at http://www.mayoclinic.com/print/mononucleosis/DS00352/DSECTION=all&METHOD=print. Accessed November 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 407-409.

Kasper DL, Braunwald E, Fauci AS, Hauser SL, Longo DL, Jameson JL eds, (2005) Harrison's Principles of Internal Medicine, 16th Edition, McGraw Hill, pp1046-1048.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007, pp 555-556.

Hess R. Mini Review: Routine Epstein-Barr Virus Diagnostics from the Laboratory, Perspective: Still Challenging after 35 Years. Journal of Clinical Microbiology, Aug. 2004, Vol. 42, No. 8., Pg. 3381–3387.