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G6PD

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Also known as: G-6-PD; RBC G6PD test
Formal name: Glucose-6-Phosphate Dehydrogenase
Related tests: CBC, Blood Smear, Reticulocyte Count, Bilirubin, RBC Count, Hemoglobin, Autohemolysis Test, Heinz Body Stain

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Wintrobe's Clinical Hematology. 12th ed. Greer J, Foerster J, Rodgers G, Paraskevas F, Glader B, Arber D, Means R, eds. Philadelphia, PA: Lippincott Williams & Wilkins: 2009. Pp 933-939.

Gersten T. (Updated 2012 February 8). Glucose-6-phosphate dehydrogenase. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003671.htm. Accessed June 2012.

(© 1995-2012). Test ID: G6PD8368 Glucose-6-Phosphate Dehydrogenase (G-6-PD), Quantitative, Erythrocytes. Mayo Clinic May Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/8368 through http://www.mayomedicallaboratories.com. Accessed June 2012.

Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency. Merck Manual for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed June 2012.

Cook, J. et. al. (Updated 2011 July). Hemolytic Anemias. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/HemolyticAnemias.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed June 2012.

Dugdale, D. (Updated 2010 March 28). Glucose-6-phosphate dehydrogenase deficiency. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000528.htm. Accessed June 2012.

(Updated 11 December 19). National Newborn Screening Status Report. National Newborn Screening and Genetics Resource Center [On-line information]. Available online at http://genes-r-us.uthscsa.edu/nbsdisorders.htm through http://genes-r-us.uthscsa.edu. Accessed June 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 502-503.

Elghetany MT, Banki K (2011): Erythrocytic disorders, in Henry's Clinical Diagnosis and Management by Laboratory Methods, 22ed. McPherson RA, Pincus MR, eds. Elsevier Saunders. Pp 557-600.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO. Pp 449-450.

(© 2004). Glucose-6-Phosphate Dehydrogenase. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_a266.jsp#1149592 through http://www.aruplab.com.

Pradell, L. (2003 January, Reviewed). G6PD deficiency. KidsHealth, Nemours Foundation [On-line information]. Available online at http://kidshealth.org/parent/general/aches/g6pd.html through http://kidshealth.org.

Lica, L. (©2001 – 2004). Glucose-6-phosphate dehydrogenase deficiency. Blueprint for Health, Blue Cross and Blue Shield of Minnesota [On-line information]. Available online at http://blueprint.bluecrossmn.com/article/gale/100084627 through http://blueprint.bluecrossmn.com.

Dhaliwal, G. et. al. (2004 June 1). Hemolytic Anemia. American Family Physician [On-line journal]. Available online at http://www.aafp.org/afp/20040601/2599.html through http://www.aafp.org.

Cutler, C. (2003 September 14, Updated). Glucose-6-phosphate dehydrogenase deficiency. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000528.htm through http://www.nlm.nih.gov.

Cutler, C. (2003 August 18, Updated). Hemolytic crisis. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003270.htm through http://www.nlm.nih.gov.

Elstrom, R. (2001 October 25, Reviewed). Glucose-6-phosphate dehydrogenase deficiency. University of Maryland Medicine [On-line information]. Available online at http://www.umm.edu/ency/article/000528.htm through http://www.umm.edu.

(© 2004). Newborn Screening Tests. March of Dimes [On-line information]. Available online at http://www.modimes.org/pnhec/298_834.asp through http://www.modimes.org.

WHO Working Group, Beutler, E. et. al. (1989). Glucose-6-phosphate dehydrogenase deficiency [64 paragraphs]. Bulletin of the World Health Organization 67 (6): 601-611. [On-line journal]. PDF available for download at http://whqlibdoc.who.int/bulletin/1989/Vol67-No6/bulletin_1989_67(6)_601-611.pdf through http://whqlibdoc.who.int.

Beutler, E. (© 1996-2004). Erythrocyte disorders: Anemias due to increased destruction of erythrocytes with enzyme deficiencies Glucose-6-phosphate dehydrogenase deficiency. G6PD Deficiency favism association [On-line article from Williams' HEMATOLOGY]. Available online at http://www.rialto.com/favism/english/index.mv?pgid=beutler_01 through http://www.rialto.com.

The Ness Foundation: What is Oxidative Stress? Available online at http://www.ness-foundation.org.uk/What-is-Oxidative-Stress.html through http://www.ness-foundation.org.uk.

Netdoctor.co.uk. Oxidative Stress. Available online at http://www.netdoctor.co.uk/focus/nutrition/facts/oxidative_stress/oxidativestress.htm through http://www.netdoctor.co.uk.

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 497-498.

Wu, A. (2006).  Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 456-457.

Ben-Joseph, E. (2006 August, Reviewed). G6PD deficiency. Nemours Foundation, KidsHealth for Parents [On-line information]. Available online at http://kidshealth.org/parent/general/aches/g6pd.html through http://kidshealth.org. Accessed on 8-27-08.

Matsui, W. (2007 February 26, Updated). Glucose-6-phosphate dehydrogenase deficiency. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000528.htm. Accessed on 8-27-08.

Henningson, C. (2007 March 22, Updated). Glucose-6-phosphate dehydrogenase. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003671.htm. Accessed on 8-27-08.

(2006 May, Reviewed). Glucose-6-phosphate dehydrogenase deficiency. Genetics Home Reference [On-line information]. Available online at http://ghr.nlm.nih.gov/condition=glucose6phosphatedehydrogenasedeficiency through http://ghr.nlm.nih.gov. Accessed on 8-27-08.

(2006 September). What is Hemolytic Anemia. NHLBI [On-line information]. Available online at http://www.nhlbi.nih.gov/health/dci/Diseases/ha/ha_whatis.html through http://www.nhlbi.nih.gov. Accessed on 8-27-08.

G6PD Deficiency Favism Association, What is G6PD Deficiency? Available online at http://www.g6pd.org/favism/english/index.mv?pgid=intro through http://www.g6pd.org. Accessed September 2008.