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eGFR

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Also known as: Calculated Glomerular Filtration Rate; cGFR
Formal name: Estimated Glomerular Filtration Rate

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Turin, T. et. al. (2013) Change in the Estimated Glomerular Filtration Rate Over Time and Risk of All-Cause Mortality. Medscape Today News from Kidney Int. v83 (4):684-691 [On-line information]. Available online at http://www.medscape.com/viewarticle/782622 through http://www.medscape.com. Accessed July 2013.

Simon, J. et. al. (2011 March). Interpreting the estimated glomerular filtration rate in primary care: Benefits and pitfalls. Cleveland Clinic Journal of Medicine v78 (3) 189-195. [On-line information]. Available online at http://www.ccjm.org/content/78/3/189.full through http://www.ccjm.org. Accessed July 2013.

(© 1995–2013). Cystatin C with Estimated GFR, Serum. Mayo Clinic Mayo Medical Laboratory Interpretive Handbook [On-line information]. Available online at http://www.mayomedicallaboratories.com/interpretive-guide/?alpha=C&unit_code=35038 through http://www.mayomedicallaboratories.com. Accessed July 2013.

(Updated 2012 July 10) For People with Diabetes or High Blood Pressure: Get Checked for Kidney Disease. National Kidney Disease Education Program [On-line information]. Available online at http://www.nkdep.nih.gov/resources/get-checked-kidney-disease.shtml through http://www.nkdep.nih.gov. Accessed July 2013.

Dugdale, D. (Updated 2011 September 19). Glomerular filtration rate. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/007305.htm through http://www.nlm.nih.gov. Accessed July 2013.

Shah, A. (Revised 2013 May). Evaluation of the Renal Patient. Merck Manual for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed July 2013.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 329-333.

Clarke, W., Editor (© 2011). Contemporary Practice in Clinical Chemistry 2nd Edition: AACC Press, Washington, DC. Pp 362-364.

McPherson, R. and Pincus, M. (© 2011). Henry's Clinical Diagnosis and Management by Laboratory Methods 22nd Edition: Elsevier Saunders, Philadelphia, PA. Pp 173-177.

National Kidney Disease Education Program. Estimating GFR. Available online at http://nkdep.nih.gov/lab-evaluation/gfr/estimating.shtml through http://nkdep.nih.gov. Accessed October 2013.

National Kidney Foundation. Cystatin C: What is its role in esimating GFR? Available online at http://www.kidney.org/professionals/tools/pdf/CystatinC.pdf through http://www.kidney.org. Accessed October 2013.

Weber, CL et al. Demystifying chronic kidney disease: Clinical caveats for the family physician. BCMJ, Vol. 50, No. 6, July, August 2008, page(s) 304-309. Available online at http://www.bcmj.org/article/demystifying-chronic-kidney-disease-clinical-caveats-family-physician through http://www.bcmj.org. Accessed January 2015.

Sources Used in Previous Reviews

National Kidney Foundation. DOQI: Clinical Practice Guidelines. Available online at http://www.kidney.org/professionals/kdoqi/guidelines through http://www.kidney.org.

National Kidney Foundation. Glomerular Filtration Rate. Available online at http://www.kidney.org/kidneydisease/ckd/knowGFR.cfm through http://www.kidney.org.

National Kidney Foundation. Kidney Learning System: GFR. Available online at http://www.kidney.org/professionals/KLS/gfr.cfm through http://www.kidney.org.

Levey et al. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Annals of Internal Medicine. 1999; 130(6):461-470.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 311-312.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 438-439.

Patel, P. (Updated 2009 August 12). Glomerular filtration rate. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/007305.htm. Accessed October 2009.

(2009 February). The Kidneys and How They Work. National Kidney and Urologic Diseases Information Clearinghouse [On-line information]. Available online at http://kidney.niddk.nih.gov/kudiseases/pubs/yourkidneys/ through http://kidney.niddk.nih.gov. Accessed October 2009.

(Reviewed 2009 April 7). Laboratory Professionals, Estimating and Reporting GFR. National Kidney Disease Education Program [On-line information]. Available online at http://www.nkdep.nih.gov/labprofessionals/estimate_report_gfr.htm through http://www.nkdep.nih.gov. Accessed October 2009.

Delgado, J. (Updated 2009 August). Renal Function Markers - Kidney Disease. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/RenalFunctionMarkers.html?client_ID=LTD# through http://www.arupconsult.com. Accessed October 2009.

(© 2007). Estimated Glomerular Filtration Rate (eGFR), in the Detection and Assessment of Chronic Kidney Disease in Adults. LabCorp Technical Review [On-line information]. PDF available for download at https://www.labcorp.com/pdf/Estimated_Glomerular_Filtration_Rate_eGFRL1137_1207_2.pdf through https://www.labcorp.com. Accessed October 2009.

(Reviewed 2007 October). Glomerular Filtration Rate, Estimated (eGFR). Quest Diagnostics Test Summary [On-line information]. Available online at http://www.questdiagnostics.com/hcp/intguide/jsp/showintguidepage.jsp?fn=TS_eGFR.htm through http://www.questdiagnostics.com. Accessed October 2009.