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Growth Hormone

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Also known as: GH; Human Growth Hormone; HGH; Somatotropin; Growth Hormone Stimulation Test; Growth Hormone Suppression Test
Formal name: Growth Hormone
Related tests: IGF-1; Growth Hormone Releasing Hormone; Cortisol; ACTH; Free T4; TSH; Glucose Tests; Prolactin; IGF BP-3

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Updated 2012 April 6). Acromegaly. National Endocrine and Metabolic Diseases Information Service. [On-line information]. Available online at http://www.endocrine.niddk.nih.gov/pubs/acro/acro.aspx through http://www.endocrine.niddk.nih.gov. Accessed August 2014.

Topiwala, S. (Updated 2012 May 31). Growth hormone test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003706.htm through http://www.nlm.nih.gov. Accessed August 2014.

Hammami, M. (Updated 2013 June 7). Growth Hormone. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2089136-overview through http://emedicine.medscape.com. Accessed August 2014.

Diaz-Thomas, A. et. al. (Updated 2014 May 12)). Gigantism and Acromegaly. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/925446-overview through http://emedicine.medscape.com. Accessed August 2014.

Rosenbloom, A. and Guevara-Aguirre, J. (Updated 2014 January 23). Growth Hormone Resistance. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/922902-overview through http://emedicine.medscape.com. Accessed August 2014.

van Bunderen, C. et. al. (2014). Efficacy and Safety of Growth Hormone Treatment in Adults With Growth Hormone Deficiency A Systematic Review of Studies on Morbidity. Medscape News from Clin Endocrinol. 2014;81(1):1-14. [On-line information]. Available online at http://www.medscape.com/viewarticle/827774 through http://www.medscape.com. Accessed August 2014.

Meikle, A. W. (Updated 2014 January). Growth Hormone Deficiency. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/GrowthHormone.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed August 2014.

(June 7, 2013) Hammami, M. Growth Hormone. Medscape Reference. Available online at http://emedicine.medscape.com/article/2089136-overview#a30 through http://emedicine.medscape.com. Accessed September 2014.

Eledrisi, MS. Growth Hormone Deficiency. Medscape. Available online at http://emedicine.medscape.com/article/120767-overview through http://emedicine.medscape.com. Accessed March 2015.

Kemp, S. Pediatric Growth Hormone Deficiency. Available online at http://emedicine.medscape.com/article/923688-overview through http://emedicine.medscape.com. Accessed March 2015.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Sadovsky, R. (2002 August 6). Are We Ready for Growth Hormone Therapy in Adults? American Family Physician, Tips form other journals [On-line journal]. Available online at http://www.aafp.org/afp/20021115/tips/10.html through http://www.aafp.org.

Growth Hormone (Human Growth Hormone, HGH, Somatotropin). ARUP's Guide to Clinical Laboratory Testing (CLT) [On-line test information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_a244.htm through http://www.aruplab.com.

Growth Hormone Information. The Hormone Foundation [On-line information]. Available online at http://www.hormone.org/learn/growth.html through http://www.hormone.org.

(2002 November 12, Updated). Growth hormone no fountain of youth, study suggests. LaurusHealth.com, Today's Headlines [Online information from Reuters Health]. Available online at http://www.laurushealth.com/healthnews/reuters//NewsStory111220023.htm through http://www.laurushealth.com.

Growth hormone tests. Hendrick Health System, AccessMed [On-line information]. Available online at http://www.hendrickhealth.org/healthy/00049860.html through http://www.hendrickhealth.org.

Ruppe, M., Reviewed (2002 February 23, Reviewed). Growth hormone. Pennhealth.com Health Illustrated Encyclopedia [On-line information]. Available online at http://www.pennhealth.com/ency/article/003706.htm through http://www.pennhealth.com.

Spengler, R. (2001 April 9, Updated). Growth Hormone. LaurusHealth.com, Medical Tests [On-line information]. Available online through http://www.laurushealth.com.

AACE Clinical Practice Guidelines for Growth Hormone Use in Adults and Children. Available for download at http://www.aace.com/clin/guidelines/hgh.pdf through http://www.aace.com.

Bernal-Mizrachi, C., Updated (2001 June 2, Updated). Growth hormone stimulation test. MEDLINEplus Health Information [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003377.htm.

Bernal-Mizrachi, C., Updated (2001 June 1, Updated). Growth hormone suppression test. MEDLINEplus [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003376.htm.

Ruppe, M. (2002 February 23, Updated). Growth hormone. MEDLINEplus [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003706.htm.

Health Resources: Neurosurgery://On-call (2000 February). Understanding Pituitary Tumors. Patient Resources, Disorder of the Month, Pituitary Tumors Feature Article [On-line information]. Available online at http://www.neurosurgery.org/health/patient/detail.asp?DisorderID=19 through http://www.neurosurgery.org.

Pituitary Overview and Acromegaly. The Hormone Foundation [On-line information]. Available online at http://www.hormone.org/learn/pituitary_1.html through http://www.hormone.org.

Anterior Pituitary Function. The Merck Manual of Diagnosis and Therapy [On-line information]. Available online at http://www.merck.com/pubs/mmanual/section2/chapter6/6c.htm through http://www.merck.com.

Bisp, K. (2001 September 13). Testing the integrity of the system - Growth potential and excess. Society for Endocrinology, Endocrine Nurses Training Course [On-line information]. Available online at http://www.endocrinology.org/sfe/training/ent01/ent01_bis.htm through http://www.endocrinology.org.

Pagana, Kathleen D. & Pagana, Timothy J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference, 8th Edition. Mosby, Inc., Saint Louis, MO. Pp. 506 – 510.

Clarke, W. and Dufour, D. R., Editors (2006). Contemporary Practice in Clinical Chemistry. AACC Press, Washington, DC. Grenache, D. and Willis, M., Chapter 31 Hypothalamic, Pituitary, and Gonadal Disorders. Pp. 351 – 363.

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp. 502 – 510.

Hurd, R. (2006 March 8, Updated). Growth Hormone. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003706.htm. Accessed on 7/21/07.

Van Voorhees, B. (2006 June 13, Updated). Growth hormone deficiency. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/001176.htm. Accessed on 7/21/07.

Hurd, R. (2006 March 13, Updated). Growth hormone stimulation test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003377.htm. Accessed on 7/21/07.

Hurd, R. (2006 March 13, Updated). Growth hormone suppression test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003376.htm. Accessed on 7/21/07.

(2007 April). Acromegaly. NIDDK. NIH Publication No. 02-3924 [On-line information]. Available online at http://www.niddk.nih.gov/health/endo/pubs/acro/acro.htm through http://www.niddk.nih.gov. Accessed September 2007.

Leukemia and Lymphoma Society. Fact Sheet: Long Term and Late Effects of Treatment for Blood Cancers [Online information]. Available for download through http://www.leukemia-lymphoma.org. Accessed October 2007.

William E. Winter, MD, FACB. Lab Tests Online adjunct board member.

Eckman, A. (Updated 2010 April 20). Growth hormone test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003706.htm. Accessed October 2010.

(© 1995-2010). Unit Code 8688: Growth Hormone, Serum. Mayo Clinic, Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/8688 through http://www.mayomedicallaboratories.com. Accessed October 2010.

Meikle, W. and Roberts, W. (Updated 2010 May). Growth Hormone Deficiency. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/GrowthHormone.html?client_ID=LTD through http://www.arupconsult.com. Accessed October 2010.

(© 2010). Growth Disorders Treatment Options, The Hormone Foundation [On-line information]. Available online at http://www.hormone.org/Growth/treatment.cfm through http://www.hormone.org. Accessed October 2010.

Savage, M. et. al. (2010 June 23). The Continuum of Growth Hormone–IGF-I Axis Defects Causing Short Stature: Diagnostic and Therapeutic Challenges. Medscape Today from Clin Endocrinol. 2010;72(6):721-728. [On-line information]. Available online at http://www.medscape.com/viewarticle/722763 through http://www.medscape.com. Accessed October 2010.

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 506-508.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 502-503.

Kronenberg, H. et. al. (© 2008). Williams Textbook of Endocrinology, 11th Edition: Saunders Elsevier, Philadelphia, PA. Pp 857-863.

Rosenbloom, Arlan L. Sex Hormone Priming for Growth Hormone Stimulation Testing in Pre- and Early Adolescent Children Is Evidence Based. Horm Res Paediatr 2011;75:78–80.