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H pylori Testing

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Also known as: H. pylori; H-pylori; H. pylori antibody test; H. pylori stool antigen test; H. pylori breath test; Urea breath test; CLO test; Rapid urease test (RUT) for H. pylori
Formal name: Helicobacter pylori
Related tests: Gastrin

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Baumann, A. and Katz, P. (Updated 2014 January 27). Helicobacter Pylori Antigen Test. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2117821-overview through http://emedicine.medscape.com. Accessed October 2014.

Santacroce, L. and Bhutani, M. (Updated 2014 September 11). Helicobacter Pylori Infection. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/176938-overview through http://emedicine.medscape.com. Accessed October 2014.

Longstreth, G.(Updated 2013 August 22). Tests for H pylori. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/007501.htm through http://www.nlm.nih.gov. Accessed October 2014.

DiMarino, M. (Revised 2014 May). Helicobacter pylori Infection. The Merck Manual Professional Edition [On-line information]. Available online through http://www.merckmanuals.com. Accessed October 2014.

(© 1995–2014). Helicobacter pylori Antibody, IgA, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/35755 through http://www.mayomedicallaboratories.com. Accessed October 2014.

(2013 November). Helicobacter pylori Infection: Test Utilization Strategies for Diagnosis. Communique, Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/articles/communique/2013/11-hpylori-infection/ through http://www.mayomedicallaboratories.com. Accessed October 2014.

Kelly, J. (2014 September 30). WHO Urges H pylori Screening to Prevent Gastric Cancer. Medscape News [On-line information]. Available online at http://www.medscape.com/viewarticle/832581 through http://www.medscape.com. Accessed October 2014.

Baron, E. et. al. (2013 July 10). A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2013 Recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM). [On-line information]. Available online through http://www.idsociety.org. Accessed October 2014.

Pagana, K. D., Pagana, T. J., and Pagana, T. N. (© 2015). Mosby's Diagnostic & Laboratory Test Reference 12th Edition: Mosby, Inc., Saint Louis, MO. Pp 494-496.

Sources Used in Previous Reviews

The Cleveland Clinic Health Information Center. Breath Test for H. pylori (Online information). Available online at http://www.clevelandclinic.org/health/. Accessed February 2008.

Pagana K, Pagana T. Mosby's Manual of Diagnostic and Laboratory Tests. 3rd Edition, St. Louis: Mosby Elsevier; 2006.

Forbes BA, Sahm DF, Weissfeld AS. Bailey & Scott's Diagnostic Microbiology 12th Edition: Mosby Elsevier, St. Louis, MO; 2007.

Chisholm SA, Owen RJ. Application of polymerase chain reaction-based assays for rapid identification and antibiotic resistance screening of Helicobacter pylori in gastric biopsies. Diagn Microbiol Infect Dis. 2008 Jan 11.

Siddique I, et. al Diagnosis of Helicobacter pylori: Improving the Sensitivity of CLOtest by Increasing the Number of Gastric Antral Biopsies. J Clin Gastroenterol. 2008 Apr;42(4):356-360.

Clinical Chemistry: Principles, Procedures, Correlations. Bishop M, Duben-Engelkirk J, Fody E, eds. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2000.

Clinical Chemistry: Theory, Analysis, and Correlations. Kaplan L, Pesce A, eds. 2nd ed. St. Louis: The C. V. Mosby Company; 1989.

National Digestive Diseases Information Clearinghouse. H. pylori and Peptic Ulcer. Available online at http://digestive.niddk.nih.gov/ddiseases/pubs/hpylori/ through http://digestive.niddk.nih.gov. Accessed June 2011.

Michael Selgrad, Arne Kandulski and Peter Malfertheiner. Helicobacter pylori: Diagnosis and Treatment: Diagnosis of Helicobacter pylori. Curr Opin Gastroenterol. 2009;25(6):549-556. Available online at http://www.medscape.com/viewarticle/711405_2 through http://www.medscape.com. Accessed June 2011.