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hCG Pregnancy

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Also known as: Pregnancy Test; Qualitative hCG; Quantitative hCG; Beta hCG; Total hCG; Total beta hCG
Formal name: Human Chorionic Gonadotropin

Were you looking instead for hCG Tumor Markers, used to help diagnose and monitor therapy for certain cancers?

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Farinde, A. (Updated 2014 July 2). Human Chorionic Gonadotropin (hCG). Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2089158-overview through http://emedicine.medscape.com. Accessed September 2014.

(Updated 2014 June 5). Pregnancy. U.S. Food and Drug Administration Medical Devices [On-line information]. Available online at http://www.fda.gov/MedicalDevices/ProductsandMedicalProcedures/InVitroDiagnostics/HomeUseTests/ucm126067.htm through http://www.fda.gov. Accessed September 2014.

Grenache, D. and Lehman, C. (Updated 2012 November). hCG Testing – hCG. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/hCG.html?client_ID=LTD through http://www.arupconsult.com. Accessed September 2014.

Rollins, G. (2012 March 8). Taking a New Look at the hCG Discriminatory Level. Clinical Laboratory Strategies [On-line information]. Available online at http://www.aacc.org/publications/strategies/archives/2012/Documents/030812CLS.pdf through http://www.aacc.org. Accessed September 2014.

Grenache, D. (2013). Identifying the Pregnant Patient, There's More to Know than "Yes" or "No." AACC Presentation [On-line information]. Available online at http://www.aacc.org/members/loc_sections/ncalifornia/LSNCMtgAnnouncements/Documents/Grenache_hCG_POC_BayChem_2013.pdf through http://www.aacc.org. Accessed September 2014.

Grenache, D. (2011). Human Chorionic Gonadotropin. Clinical Chemistry Trainee Council Pearls of Laboratory Medicine [On-line information]. Available online at http://www.aacc.org/publications/clin_chem/ClinChemTrainCouncil/pearls/Documents/Pearls_Grenache_Script.pdf through http://www.aacc.org. Accessed September 2014.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 558-560.

Manual of Laboratory and Diagnostic Tests, 8th ed. (2009) Lippincott Williams & Wilkins: Philadelphia.

Sepilian V (September 2, 2014). Ectopic Pregnancy. Medscape Reference. Available online at http://emedicine.medscape.com/article/2041923-overview through http://emedicine.medscape.com. Accessed September 2014.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

(2003 June 23). Free Beta-Subunit of Human Chorionic Gonadotropin (Free b-hCG) Enzyme Immunoassay Test Kit. BioCheck, Inc. [On-line package insert]. PDF available for download at http://www.biocheckinc.com/inserts/bc-1023_fbhcg.pdf through http://www.biocheckinc.com.

Newberger, D. (2000 August 15). Down Syndrome: Prenatal Risk Assessment and Diagnosis. American Family Physician [On-line journal]. Available online at http://www.aafp.org/afp/20000815/825.html through http://www.aafp.org.

Qin, Q., et. al. (2002). Point-of-Care Time-resolved Immunofluorometric Assay for Human Pregnancy-associated Plasma Protein A: Use in First-Trimester Screening for Down Syndrome [Pages 1-3 of 20]. Clinical Chemistry 48:473-483 [On-line journal]. Available online at http://www.clinchem.org/cgi/content/full/48/3/473 through http://www.clinchem.org.

(2000). Down Syndrome Screening. NTD Laboratories, Inc. [On-line information]. Available online at http://www.ntdlabs.com/dscreen.html through http://www.ntdlabs.com.

Hoffman, B. and Johnson, J. (2004). Toronto's Mount Sinai Hospital offers First-Trimester Screening Across Ontario. Healthcare Quarterly 7(2). PDF available for download at http://www.mountsinai.on.ca/Resources/HQ72MtSinaiProfile.pdf through http://www.mountsinai.on.ca.

Paralloi, A. (August 13, 2003, Edited) Second Trimester Maternal Serum Screening Programmes for the Detection of Down's Syndrome. Geneva Foundation for Medical Education and Research [On-line information, 8th Post Graduate Course]. Available online through http://www.gfmer.ch.

First Trimester Prenatal Screening. Alfigen, The Genetics Institute, Laboratory Services [On-line information]. Available online at http://www.alfigen.com/laboratory_4_3.html through http://www.alfigen.com.

(1999 March 18). Prenatal Program Pushes the Frontiers of Diagnosis. Cedars-Sinai Medical Center [On-line News release]. Available online at http://www.newswise.com/p/articles/view?id=PREDIAG.CED through http://www.newswise.com.

Free beta hCG [I-125] IRMA kit (RK-820CT) - coated tube. IZOTOP [On-line test information]. Available online at http://www.izotop.hu/print/rk820c.htm through http://www.izotop.hu.

Beta-hCG, Serum Quantitative=. ARUP's Guide to Clinical laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_al98.jsp#1145363 through http://www.arup-lab.com.

Spencer, K. What is Free Beta hCG. Down Syndrome Screening Research [On-line information]. Available online at http://ourworld.compuserve.com/homepages/kevin_spencer/freebeta.htm through http://ourworld.compuserve.com.

Ultra-Screen First Trimester Prenatal Screening. Center for Medical Genetics [On-line brochure]. PDF available for download at http://www.geneticstesting.com/pdfs/UltraScreen_Brochure.pdf through http://www.geneticstesting.com.

Vankrieken, L., et. al. (2000). HCG and Subunits: DPC Assay Specificities and Clinical Utility in Obstetrical Care and Oncology. Immulite [DPC Technical Report]. PDF available for download through http://www.dpcweb.com.

Framarin, A. (2003) First-trimester prenatal screening for Down syndrome and other aneuploidies. Agence d’e’valuation des technologies et des modes d’intervention en sante’ [On-line report, Quebec]. PDF available for download through http://www.aetmis.gouv.qc.ca.

(2000). What is Ultra-Screen. NTD Laboratories, Inc. [On-line information]. Available online at http://www.ntdlabs.com/ultraphys.html through http://www.ntdlabs.com.

Shaskan, J. (2004 May 31). Amniocentesis and CVS Tests Decline Despite Increase in Number of Older Mothers. ACOG [On-line news release]. Available online at http://www.acog.org/from_home/publications/press_releases/nr05-31-04-1.cfm through http://www.acog.org.

Wu, A. (2006). Tietz Clinical Guide to Laboratory Tests, Fourth Edition. Saunders Elsevier, St. Louis, Missouri. Pp 252-255.

Vorvick, L. (Updated 2010 November 21) HCG blood test – qualitative. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003509.htm. Accessed March 2011.

Gaufberg, S. (Updated 2010 April 16) Early Pregnancy Loss. eMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/795085-overview through http://emedicine.medscape.com. Accessed March 2011.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 558-560.

Grenache, D. et. al. (Updated 2011 January) hCG Testing – hCG. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/hCG.html?client_ID=LTD through http://www.arupconsult.com. Accessed March 2011.

(© 1995–2011). Unit Code 80678: Human Chorionic Gonadotropin (hCG), Quantitative, Pregnancy, Serum Mayo Clinic, Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/80678 through http://www.mayomedicallaboratories.com. Accessed March 2011.

Ann M. Gronowski, Corinne R. Fantz, Curtis A. Parvin, Lori J. Sokoll, Carmen L. Wiley, Mark H. Wener, and David G. Grenache. Use of Serum FSH to Identify Perimenopausal Women with Pituitary hCG. Clin. Chem., Apr 2008; 54: 652 - 656.

One-Year Experience with Day-of-Surgery Pregnancy Testing Before Elective Orthopedic Procedures. Kahn, RL et al. Anesthesia & Analgesia April 2008. Vol. 106. No. 4 Pp 1127-1131.