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hs-CRP

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Also known as: hsCRP; High-sensitivity CRP; Ultra-sensitive CRP; Cardiac CRP; CRP for heart disease
Formal name: High-sensitivity C-reactive Protein

Were you looking for the CRP test, used to evaluate general inflammation?

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Lutsep, H. and Stetka, B. (2015 January 16). New Stroke Prevention Guidelines: A Quick and Easy Guide. Medscape Neurology [On-line information]. Available online at http://www.medscape.com/viewarticle/838140 through http://www.medscape.com. Accessed February 2015.

Delgado, J. et. al. (2014 November). Cardiovascular Disease (Non-traditional Risk Markers) - Risk Markers - CVD (Non-traditional). ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/CVDRiskMarkerNontrad.html?client_ID=LTD through http://www.arupconsult.com. Accessed February 2015.

Yousuf, O. et. al. (2013). High-Sensitivity C-Reactive Protein and Cardiovascular Disease, A Resolute Belief or an Elusive Link? Medscape Multispecialty from J Am Coll Cardiol. 2013;62(5):397-408 [On-line information]. Available online at http://www.medscape.com/viewarticle/808448 through http://www.medscape.com. Accessed February 2015.

(2014 August 4). Who Is at Risk for Atherosclerosis? National Heart Lung and Blood Institute [On-line information]. Available online at http://www.nhlbi.nih.gov/health/health-topics/topics/atherosclerosis/atrisk through http://www.nhlbi.nih.gov. Accessed February 2015.

Teitel, A. (Updated 2013 February 11). C-reactive protein. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003356.htm through http://www.nlm.nih.gov. Accessed February 2015.

Whelton, S. et. al. (2013). Elevated High-sensitivity C-reactive Protein as a Risk Marker of the Attenuated Relationship Between Serum Cholesterol and Cardiovascular Events at Older Age, The ARIC Study. Medscape Multispecialty from Am J Epidemiol. 2013;178(7):1076-1084 [On-line information]. Available online at http://www.medscape.com/viewarticle/811811 through http://www.medscape.com. Accessed February 2015.

Pagana, K. D., Pagana, T. J., and Pagana, T. N. (© 2015). Mosby's Diagnostic & Laboratory Test Reference 12th Edition: Mosby, Inc., Saint Louis, MO. Pp 306-307.

(March 1, 2012) Assessing Cardiovascular Risk: Guideline Synthesis. Agency for Healthcare Research and Quality (AHRQ). Available online at http://www.medscape.com/viewarticle/759314_4 through http://www.medscape.com. Accessed March 4, 2015.

Sources Used in Previous Reviews

American College of Cardiology clinical trials pages. Available online at http://www.acc.org/education/online/trials/acc2001/prince.htm through http://www.acc.org.

Santa Fe Colloquium on Preventive Cardiovascular Therapy. Available online at http://www.acc.org/education/online/sante%5Ffe/ridker.htm through http://www.acc.org.

Ridker PM, Stampfer MJ, Rifai N. Novel risk factors for atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral arterial disease. JAMA 2001; 285:2481-2485. (May 16, 2001).

Ridker PM, Hennekens CH, Buring JE, and Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. NEJM 2000; 342:836-843. (March 23, 2000).

ARUP Lab fact sheet. Available online at http://www.aruplab.com/guides/clt through http://www.aruplab.com.

American Heart Association Journal Report 01/28/2003. AHA/CDC panel issues recommendations on CRP testing. Available online at http://www.americanheart.org/presenter.jhtml?identifier=3007984 through http://www.americanheart.org.

MedlinePlus Medical Encyclopedia. C-reactive protein. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003356.htm. Accessed December 2008.

The Evolving Role of High-Sensitivity C-Reactive Protein in Cardiovascular Health: An Expert Interview With Paul M. Ridker, MD. Posted 01/03/2006. Available online at http://www.medscape.com/viewarticle/519642 through http://www.medscape.com. Accessed December 2008.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 319-321.

(© 1995-2012). Test ID: HSCRP C-Reactive Protein, High Sensitivity, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/82047 through http://www.mayomedicallaboratories.com. Accessed May 2012.

Devaraj, S. and Lin, J. (Updated 2012 February 24). High-Sensitivity C-Reactive Protein. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2094831-overview#showall through http://emedicine.medscape.com. Accessed May 2012.

Delgado, J. et. al. (Updated 2011 April). Cardiovascular Disease (Non-traditional Risk Markers) - Risk Markers - CVD (Non-traditional). ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/CVDRiskMarkerNontrad.html?client_ID=LTD through http://www.arupconsult.com. Accessed May 2012.

Davidson, M. (2011 May 19). hs-CRP: What Is Proven and Unproven? Medscape Today from Circulation. 2011;123:731-738 [On-line information]. Available online at http://www.medscape.com/viewarticle/742591 through http://www.medscape.com. Accessed May 2012.

Clarke, W., Editor (© 2011). Contemporary Practice in Clinical Chemistry 2nd Edition: AACC Press, Washington, DC. Pg 239.

Greenland P, et al. 2010 ACCF/AHA Guideline for Assessment of Cardiovascular Risk in Asymptomatic Adults: Executive Summary, A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Available online at http://circ.ahajournals.org/content/122/25/2748.full#sec-20 through http://circ.ahajournals.org. Accessed May 2012.