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Also known as: LPS
Formal name: Lipase
Related tests: Amylase, Trypsin, Trypsinogen

The Test Sample

What is being tested?

Location of the pancreas

Lipase is one of several enzymes produced by the pancreas to help digest dietary fats. This test measures the amount of lipase in the blood.

Lipase is transported through the pancreatic duct and into the first part of the small intestine (duodenum), where it helps break down dietary triglycerides (a form of fat) into fatty acids. The pancreas is the primary source of lipase, but cells in other areas of the body involved with digestion and nutrient absorption also produce lipase, including those in the tongue, stomach and liver.

Lipase is usually present in the blood in small quantities. When cells in the pancreas are injured, like with pancreatitis, or when the pancreatic duct is blocked by a gallstone or, in rare cases, by a pancreatic tumor, increased amounts of lipase enter the blood and result in higher concentrations in the blood.

How is the sample collected for testing?

A blood sample is obtained by inserting a needle into a vein in the arm.

NOTE: If undergoing medical tests makes you or someone you care for anxious, embarrassed, or even difficult to manage, you might consider reading one or more of the following articles: Coping with Test Pain, Discomfort, and Anxiety, Tips on Blood Testing, Tips to Help Children through Their Medical Tests, and Tips to Help the Elderly through Their Medical Tests.

Another article, Follow That Sample, provides a glimpse at the collection and processing of a blood sample and throat culture.

Is any test preparation needed to ensure the quality of the sample?

No test preparation is needed.