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Lyme Disease Tests

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Also known as: Lyme Antibodies Detection; Lyme Antibodies IgM/IgG by Western Blot
Formal name: Borrelia burgdorferi Antibodies, IgM/IgG; Borrelia burgdorferi DNA Detection by PCR
Related tests: CSF Analysis

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

Devkota, B. (2014 January 16). Lyme Disease Serology. Medscape Drugs & Diseases [On-line information]. Available online at http://emedicine.medscape.com/article/2094578-overview. Accessed 07/18/15.

Vyas, J. (2014 February 3). Lyme disease blood test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003554.htm. Accessed 07/18/15.

(2015 March 26, Updated). Lyme Disease, Two-step Laboratory Testing Process. Centers for Disease Control and Prevention [On-line information]. Available online at http://www.cdc.gov/lyme/diagnosistesting/labtest/twostep/index.html. Accessed 07/18/15.

Krause, P. and Bockenstedt, L. (2013). Lyme Disease and the Heart, Cardiology Patient Page. Circulation. 2013; 127: e451-e454. [On-line information]. Available online at http://circ.ahajournals.org/content/127/7/e451.full. Accessed 07/18/15.

Couturier, M. and Hillyard, D. (2015 May, Updated). Borrelia burgdorferi - Lyme Disease. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/LymeDisease.html?client_ID=LTD. Accessed 07/18/15.

(© 1995-2015). Lyme Disease Serology, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/9129. Accessed 07/18/15.

Barclay, L. (2015 June 25). Alternative Lab Tests May Not Reliably Diagnose Lyme Disease. Medscape Multispecialty [On-line information]. Available online at http://www.medscape.com/viewarticle/846997. Accessed 07/18/15.

(2013 May). Lyme Disease: Who Should Be Tested and What Test Should Be Ordered? Mayo Clinic Mayo Medical Laboratories Communiqué [On-line information]. Available online at http://www.mayomedicallaboratories.com/articles/communique/2013/05-new-ehrlichia-species/utiliz.html. Accessed 2015.

Pagana, K. D., Pagana, T. J., and Pagana, T. N. (© 2015). Mosby's Diagnostic & Laboratory Test Reference 12th Edition: Mosby, Inc., Saint Louis, MO. Pp 613-614.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Wormser GP, et al. The Clinical Assessment, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: Clinical Practice Guidelines by the Infectious Diseases Society of America, Clinical Infectious Diseases 2006;43:1089–1134. Available online at http://www.journals.uchicago.edu/doi/full/10.1086/508667?cookieSet=1. Accessed June 2009.

(May 1, 2008) Press Release: Agreement Ends Lyme Disease Investigation by Connecticut Attorney General. Available online at http://www.idsociety.org/Content.aspx?id=11182. Accessed June 2009.

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 632-633.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 1538.

Forbes, B. et. al. (© 2007). Bailey & Scott's Diagnostic Microbiology, 12th Edition: Mosby Elsevier Press, St. Louis, MO. Pp 537-539.

(Modified 2009 January 27). Learn About Lyme Disease. Centers for Disease Control and Prevention [On-line information]. Available online at http://www.cdc.gov/ncidod/dvbid/lyme/. Accessed March 2009.

(Reviewed 2008 October 7). Lyme Disease Diagnosis. Centers for Disease Control and Prevention [On-line information]. Available online at http://www.cdc.gov/ncidod/dvbid/lyme/ld_humandisease_diagnosis.htm. Accessed March 2009.

Editorial staff (Updated 2008 May). Lyme Disease. Familydoctor.org [On-line information]. Available online at http://familydoctor.org/online/famdocen/home/common/infections/common/bacterial/257.printerview.html. Accessed March 2009.

(2007 June 27). Beware of Ticks … & Lyme Disease. U.S. Food and Drug Administration [On-line information]. Available online at http://www.fda.gov/consumer/updates/lymedisease062707.html. Accessed March 2009.

(Reviewed 2008 October 8). Lyme Disease Treatment and Prognosis Centers for Disease Control and Prevention [On-line information]. Available online at http://www.cdc.gov/ncidod/dvbid/lyme/ld_humandisease_treatment.htm. Accessed March 2009.

Mayo Clinic Staff (2008 May 2). Lyme disease. MayoClinic.com [On-line information]. Available online at http://www.mayoclinic.com/print/lyme-disease/DS00116/METHOD=print&DSECTION=all. Accessed March 2009.

(2008 July). Lyme Disease - The Facts The Challenge. National Institute of Allergy and Infectious Diseases, National Institute of Arthritis and Musculoskeletal and Skin Diseases [On-line information]. PDF available for download at http://www3.niaid.nih.gov/topics/lymeDisease/PDF/LymeDisease.pdf. Accessed March 2009.

(© 2009). Lyme Disease: A Patient's Guide. American College of Physicians [On-line information]. Available online at http://www.acponline.org/clinical_information/resources/lyme_disease/patient/. Accessed March 2009.

Edlow, J. (Updated 2008 December 12). Tick-Borne Diseases, Lyme. Emedicine [On-line information]. Available online at http://emedicine.medscape.com/article/786767-overview. Accessed March 2009.

Levin, M. (Updated 2012 March 15). Lyme disease antibody. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003554.htm. Accessed June 2012.

(Updated 2011 November 15). Lyme Disease, Laboratory Testing. CDC [On-line information]. Available online at http://www.cdc.gov/lyme/diagnosistreatment/LabTest/. Accessed June 2012.

Cook, J. et. al. (Updated 2011 June). Borrelia burgdorferi - Lyme Disease ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/LymeDisease.html?client_ID=LTD. Accessed June 2012.

(Updated 2012 March 7). Lyme Disease Frequently Asked Questions (FAQ). CDC [On-line information]. Available online at http://www.cdc.gov/lyme/faq/index.html. Accessed June 2012.

(Updated 2011 March 29). Lyme Disease. National Institute of Allergy and Infectious Diseases [On-line information]. Available online at http://www.niaid.nih.gov/topics/lymedisease/understanding/pages/intro.aspx. Accessed June 2012.

(© 2012). Lyme Disease: A Patient's Guide, Diagnosis. American College of Physicians [On-line information]. Available online at http://www.acponline.org/clinical_information/resources/lyme_disease/patient/diagnosis.htm. Accessed June 2012.

Meyerhoff, J. (Updated 2011 September 27). Lyme Disease. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/330178-overview. Accessed June 2012.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 652-653.

Centers for Disease Control and Prevention. Frequently Asked Questions – Lyme Disease. Available online at http://www.cdc.gov/lyme/faq/index.html#accurate. Accessed July 2012.

Centers for Disease Control and Prevention. Transmission – Lyme Disease. Available online at http://www.cdc.gov/Lyme/transmission/index.html. Accessed July 2012.

Centers for Disease Control and Prevention. Post-Treatment Lyme Disease Syndrome. Available online at http://www.cdc.gov/lyme/postLDS/index.html. Accessed July 2012.