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Methotrexate

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Also known as: MTX [Often referred to by brand name (see MedlinePlus Drug Information)]
Formal name: Methotrexate

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Methotrexate. American Cancer Society. Available online at http://www.cancer.org/treatment/treatmentsandsideeffects/guidetocancerdrugs/methotrexate through http://www.cancer.org. Last revised December 29, 2011. Accessed January 10, 2014.

Methotrexate (Rheumatrex, Trexall). American College of Rheumatology. Available online at http://www.rheumatology.org/Practice/Clinical/Patients/Medications/Methotrexate_(Rheumatrex,_Trexall)/ through http://www.rheumatology.org. Last updated May 2012. Accessed January 10, 2014.

Methotrexate for psoriasis. WebMd. Available online at http://www.webmd.com/skin-problems-and-treatments/psoriasis/methotrexate-for-psoriasis through http://www.webmd.com. Last updated November 9, 2010. Accessed January 10, 2014.

Methotrexate (Injection Route, Subcutaneous Route). Mayo Clinic. Available online at http://www.mayoclinic.org/drugs-supplements/methotrexate-injection-route-subcutaneous-route/description/DRG-20064776 through http://www.mayoclinic.org. Last updated December 1, 2013. Accessed January 10, 2014.

Sources Used in Previous Reviews

(Revised 2009 April 1). Methotrexate. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682019.html. Accessed April 2010.

(Reviewed 2008 September 1). Methotrexate Injection. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682018.html. Accessed April 2010.

(Revised 2009 July). Patient Education, METHOTREXATE – ORAL. Medscape [On-line information]. Available online through http://www.medscape.com. Accessed April 2010.

Rotondo, N. (2008 August 13). When Is it Appropriate to Use Methotrexate for Ectopic Pregnancy in the Emergency Department? Medscape Today [On-line information]. Available online at http://www.medscape.com/viewarticle/576935 through http://www.medscape.com. Accessed April 2010.

Ranganathan, P. (2008 July 14). An Update on Methotrexate Pharmacogenetics in Rheumatoid Arthritis. Medscape Today from Pharmacogenomics. 2008;9(4):439-451. [On-line information]. Available online at http://www.medscape.com/viewarticle/576224 through http://www.medscape.com. Accessed April 2010.

(Updated 2009 November 1). Methotrexate (Oral Route, Injection Route). MayoClinic.com [On-line information]. Available online at http://www.mayoclinic.com/health/drug-information/DR600919 through http://www.mayoclinic.com. Accessed April 2010.

Brauna, J. and Rau, R. (2009 July 29). An Update on Methotrexate. Medscape from Curr Opin Rheumatol. 2009;21(3):216-223.[On-line information]. Available online at http://www.medscape.com/viewarticle/706105 through http://www.medscape.com. Accessed April 2010.

Cannon, M. (Updated 2009 August). Methotrexate (Rheumatrex, Trexall). American College of Rhematology [On-line information]. PDF available for download at http://www.rheumatology.org/practice/clinical/patients/medications/methotrexate.pdf through http://www.rheumatology.org. Accessed April 2010.

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 361-364.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 462-463.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 1400-1403.