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Parietal Cell Antibody

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Also known as: Gastric Parietal Cell Antibody; Anti-parietal Cell Antibody; Anti-GPA; AGPA; APCA
Formal name: Gastric Parietal Cell Antibody, IgG

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

2017 review performed by Bereneice Madison, PhD, MT(ASCP) and the Editorial Review Board.

Pan XF, Gu J, and ZY Shan. 2015. Type 1 Diabetic Populations Have an Increased Prevalence of Parietal Cell Antibody. A Systematic Review and Meta-Analysis. Medicine 94: 38, 2015.

Toh Ban-Hock 2016. Pathophysiology and laboratory diagnosis of pernicious anemia. Immunol Res DOI 10.1007/s12026-016-8841-7.

Bizzaro N and A Antico 2014. Diagnosis and classification of pernicious anemia. Autoimmunity Reviews 13: 565–568.

(July 6, 2016) Zayouna N. Atrophic Gastritis. Medscape. Available online at http://emedicine.medscape.com/article/176036-overview#a5. Accessed May 2017.

(Updated: 11/28/2016) Genetic and Rare Diseases Information Center. Autoimmune atrophic gastritis. Available online at https://rarediseases.info.nih.gov/diseases/10310/autoimmune-atrophic-gastritis. Accessed May 2017.

Sources Used in Previous Reviews

Eisner, T. (Updated 2012 February 5). Antiparietal cells antibodies test. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003351.htm. Accessed July 2013.

(© 1995–2013). Parietal Cell Antibodies, IgG, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/83728. Accessed July 2013.

Frank, E. (Updated 2013 July). Megaloblastic Anemia. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/MegaloblasticAnemia.html?client_ID=LTD. Accessed July 2013.

Schick, P. (Updated 2012 February 24). Megaloblastic Anemia. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/204066-overview. Accessed July 2013.

Cohen, S. (Updated 2012 February). Gastritis. Merck for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed July 2013.

What Is Pernicious Anemia? National Heart Lung and Blood Institute [On-line information]. Available online at http://www.nhlbi.nih.gov/health/health-topics/topics/prnanmia/. Accessed July 2013.

Schick, P. and Conrad, M. (Updated 2013 February 27). Pernicious Anemia. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/204930-overview. Accessed July 2013.

Gersten, T. (Updated 2012 February 8). Pernicious anemia. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000569.htm. Accessed July 2013.

(© 1995–2013). Intrinsic Factor Blocking Antibody, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/9335. Accessed July 2013.

Andres, E. and Serraj, K. (2012 September 10). Optimal management of pernicious anemia. J Blood Med. v3: 97–103. [On-line information]. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441227/. Accessed July 2013.

Sepulveda, A. and Mukherjee, S. (Updated 2012 September 27). Atrophic Gastritis. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/176036-overview#showall. Accessed July 2013.

Mukherjee, S. and Sepulveda, A. (Updated 2012 March 29). Chronic Gastritis. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/176156-overview. Accessed July 2013.

Lahner, E. and Annibale, B. (2009 November 7). Pernicious anemia: New insights from a gastroenterological point of view. World J Gastroenterol v15 (41): 5121–5128. [On-line information]. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773890/. Accessed July 2013.

Mayo Clinic Staff (2011 March 4). Vitamin deficiency anemia. Mayo Clinic [On-line information]. Available online at http://www.mayoclinic.com/health/vitamin-deficiency-anemia/DS00325. Accessed July 2013.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 826-827.