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Prealbumin

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Also known as: Thyroxine-binding Prealbumin
Formal name: Transthyretin
Related tests: C-Reactive Protein

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Johnson, A. (2007). Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflammation and malnutrition. Clinical Chemistry and Laboratory Medicine. PDF available for download at http://www.ifcc.org/media/148186/CPP%20ClinChemLabMed%20200745419426.pdf through http://www.ifcc.org. Accessed May 2013.

Parrish, C.R. (2006). Serum Proteins as Markers of Nutrition: What are we treating? Nutrition Issues in Gastroenterology. PDF available for download through http://www.medicine.virginia.edu. Accessed May 2013.

Shenkin A. Serum Prealbumin: Is It a Marker of Nutritional Status or of Risk of Malnutrition? Clin Chem Dec 2006 vol. 52 no. 12 2177-2179. Available online at http://www.clinchem.org/content/52/12/2177.full through http://www.clinchem.org. Accessed March 2013.

Beck F. Prealbumin: A Marker for Nutritional Evaluation. Am Fam Physician. 2002 Apr 15;65(8):1575-1579. Available online at http://www.aafp.org/afp/2002/0415/p1575.html through http://www.aafp.org. Accessed May 2013.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007, Pp 235-236.

Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Burtis CA, Ashwood ER, Bruns DE, eds. 4th edition, St. Louis: Elsevier Saunders; 2006, Pg 563.

Pagana and Pagana. Mosby's Manual of Diagnostic and Laboratory Tests. Fourth edition. Pp. 424-427.

Consensus Statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition: Characteristics Recommended for the Identification and Documentation of Adult Malnutrition (Undernutrition). Jane V. White, PhD, RD, FADA; Peggi Guenter, PhD, RN; Gordon Jensen, MD, PhD, FASPEN; Ainsley Malone, MS, RD, CNSC; Marsha Schofield, MS, RD; the Academy Malnutrition Work Group; the A.S.P.E.N. Malnutrition Task Force; and the A.S.P.E.N. Board of Directors. J Acad Nutr Diet. 2012;112:730-738.

Sources Used in Previous Reviews

The National Kidney Foundation: Kidney Disease Outcomes Quality Initiative. Available online at http://www.kidney.org/professionals/doqi/guidelines/nut_a04.html through http://www.kidney.org.

Holland DC, Meers C, Lawlor ME, Lam M. Serial prealbumin levels as predictors of outcomes in a retrospective cohort of peritoneal and hemodialysis patients. Journal of Renal Nutrition, July 2001, 11(3).

National Kidney Foundation Work Group, Committee: National Kidney Foundation-Kidney Disease Outcomes Quality Initiative. Clinical practice guidelines for nutrition in chronic renal failure. American Journal of Kidney Disease, June 2000, 35(6 Suppl 2): S1-140.

Clinical Guide to Laboratory Tests. 3rd ed. Tietz N, ed. Philadelphia: W.B. Saunders & Co; 1995: 608-609.

Frey RJ. Anorexia nervosa. Gale Encyclopedia of Medicine. Gale Research, 1999.

Larry A. Broussard, PhD. Clinical Laboratory Sciences, LSU Health Sciences Center, New Orleans, LA.

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 755-756.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 197.

Banh, L. (2006 October). Serum Proteins as Markers of Nutrition: What Are We Treating? Practical Gastroenterology [On-line information]. PDF available for download at http://www.healthsystem.virginia.edu/internet/digestive-health/nutritionarticles/BanhArticle.pdf through http://www.healthsystem.virginia.edu. Accessed June 2009.

Huckleberry, Y. (2004 May 03). Nutritional Support and the Surgical Patient. Medscape Today from American Journal of Health-System Pharmacy [On-line information]. Available online at http://www.medscape.com/viewarticle/474066 through http://www.medscape.com. Accessed June 2009.

Beck, F. and Rosenthal, T. (2002 April 15). Prealbumin: A Marker for Nutritional Evaluation. American Family Physician [On-line information]. Available online at http://www.aafp.org/afp/20020415/1575.html through http://www.aafp.org. Accessed June 2009.

Cassels, C. (2005 December 20). Hemodialysis, Prealbumin an independent predictor of mortality/morbidity. Medscape Medical News [On-line information]. Available online at http://www.medscape.com/viewarticle/538923 through http://www.medscape.com. Accessed June 2009.