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Thyroglobulin

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Also known as: Tg
Formal name: Thyroglobulin, Serum or Plasma

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Hershman, J. (Revised 2012 May). Overview of Thyroid Function. Merck Manual for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed August 2013.

(© 1995-2013). Thyroglobulin, Tumor Marker, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/83069 through http://www.mayomedicallaboratories.com. Accessed August 2013.

Poduval, J. (Updated 2012 October 5). Thyroglobulin. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2089532-overview through http://emedicine.medscape.com. Accessed August 2013.

Chadwick, B. et. al. (Updated 2013 May). Thyroid Cancer. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/ThyroidCancer.html?client_ID=LTD#tabs=0 through http://www.arupconsult.com. Accessed August 2013.

(Revised 2013 January 17) How is thyroid cancer diagnosed? American Cancer Society [On-line information]. Available online at http://www.cancer.org/cancer/thyroidcancer/detailedguide/thyroid-cancer-diagnosis through http://www.cancer.org. Accessed August 2013.

(2010 January). Thyroid Function Tests. National Endocrine and Metabolic Diseases Information Service [On-line information]. Available online at http://www.endocrine.niddk.nih.gov/pubs/thyroidtests/thyroidtests_508.pdf through http://www.endocrine.niddk.nih.gov. Accessed August 2013.

Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 934-935.

Clarke, W., Editor (© 2011). Contemporary Practice in Clinical Chemistry 2nd Edition: AACC Press, Washington, DC. Pp 501-502.

McPherson, R. and Pincus, M. (© 2011). Henry's Clinical Diagnosis and Management by Laboratory Methods 22nd Edition: Elsevier Saunders, Philadelphia, PA. Pp 378-379.

Spencer C. Assay of thyroid hormones and related substances. Thyroid Disease Manager. Pp 1-93. Jan 1, 2013. Available online at http://www.thyroidmanager.org/chapter/assay-of-thyroid-hormones-and-related-substances/ through http://www.thyroidmanager.org. Accessed August 2013.

Sources Used in Previous Reviews

Thomas, Clayton L., Editor (1997). Taber's Cyclopedic Medical Dictionary. F.A. Davis Company, Philadelphia, PA [18th Edition].

Pagana, Kathleen D. & Pagana, Timothy J. (2001). Mosby's Diagnostic and Laboratory Test Reference 5th Edition: Mosby, Inc., Saint Louis, MO.

Schlumberger, M. and Baudin, E. (1998). Serum Thyroglobulin determination in the follow-up of patients with differentiated thyroid carcinoma. European Journal of Endocrinology [On-line journal], vol (138) Pp 249-252. PDF available for download at http://www.eje.org/eje/138/0249/1380249.pdf through http://www.eje.org.

What is Thyroglobulin? John Hopkins Thyroid Tumor Center [On-line information]. Available online through http://www.thyroid-cancer.net.

Spencer, C. Thyroglobulin (Tg) and Tg Antibody (TgAb) Testing for Patients Treated for Thyroid Cancers. Thyroid Cancer Survivors' Association, Inc. [On-line article]. Available online at http://www.thyca.org/thyroglobulin.htm through http://www.thyca.org.

ARUP. Thyroglobulin and Thyroglobulin Antibody. ARUP lab [On-line testing information]. Available online at http://www.aruplab.com/guides/clt/tests/clt_215b.htm through http://www.aruplab.com.

ACS (2001 July 5). All About Thyroid Cancer, Detailed Guide. American Cancer Society [On-line information]. Available online at http://www.cancer.org/eprise/main/docroot/cri/cri_2_3x?dt=43 through http://www.cancer.org.

MEDLINEplus (2001 November 23). Antithyroglobulin antibody. MEDLINEplus [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003557.htm through http://www.nlm.nih.gov.

ATA (2002). Cancer of the Thyroid. The American Thyroid Association [On-line information]. Available online at http://www.thyroid.org/resources/patients/brochures/thyroid_cancer.html through http://www.thyroid.org.

(© 2005). Cancer of the Thyroid. American Thyroid Association [On-line information]. PDF available for download at http://www.thyroid.org/patients/brochures/ThyroidCancer_brochure.pdf through http://www.thyroid.org.

Whitley, RJ and Ain, KB (2004). Thyroglobulin: a specific serum marker for the management of thyroid carcinoma. Medscape from Clin Lab Med. 2004; 24(1):29-47 (ISSN: 0272-2712) [On-line Abstract] Available online at http://www.medscape.com/medline/abstract/15157556?queryText=thyroglobulin through http://www.medscape.com.

Liebert, M.A. (2003 June 05). Thyroid Tests for the Clinical Biochemist and Physician Thyroglobulin (Tg) Measurement. Medscape from Thyroid 13(1):57-67, 2003. [On-line information]. Available online at http://www.medscape.com/viewarticle/452669_print through http://www.medscape.com.

(© 2006). Thyroglobulin and Thyroglobulin Antibody. ARUP's Guide to Clinical Laboratory Testing [On-line information]. Available online at http://www.arup-lab.com/guides/clt/tests/clt_249b.jsp#1149079 through http://www.arup-lab.com.

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 916-918.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 372.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 1030-1031.

(Revised 2009 May 14). How Is Thyroid Cancer Diagnosed? American Cancer Society [On-line information]. Available online at http://www.cancer.org/docroot/cri/content/cri_2_4_3x_how_is_thyroid_cancer_diagnosed_43.asp?sitearea=&level= through http://www.cancer.org. Accessed October 2009.

Grebe, S. (2009 March 25). Diagnosis and Management of Thyroid Carcinoma: A Focus on Serum Thyroglobulin. Medscape Today from Expert Review of Endocrinology and Metabolism [On-line information]. Available online at http://www.medscape.com/viewarticle/586810 through http://www.medscape.com. Accessed October 2009.

Hershman, J. (Reviewed 2008 June). Thyroid Disorders, Introduction. Merck Manual for Healthcare Professionals [On-line information]. Available online at http://www.merck.com/mmpe/sec12/ch152/ch152a.html?qt=thyroglobulin&alt=sh through http://www.merck.com. Accessed October 2009.

Hoofnagle, A. and Wener, M. H. (2006 December). Serum thyroglobulin: a model of immunoassay imperfection. Clinical Laboratory International, CLI-Online.com v8 [On-line information]. PDF available for download at http://www.cli-online.com/fileadmin/artimg/serum-thyroglobulin-a-model-of-immunoassay-imperfection.pdf through http://www.cli-online.com. Accessed October 2009.