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TIBC, UIBC, and Transferrin

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Also known as: Iron Binding Capacity; IBC; Serum Iron-Binding Capacity; Siderophilin
Formal name: Total Iron Binding Capacity; Unsaturated Iron Binding Capacity; Transferrin; Transferrin Saturation

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NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used.

Sources Used in Current Review

Gersten, T. (Updated 2012 February 8). Total iron binding capacity. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003489.htm. Accessed April 2013.

(© 1995-2013). Iron and Total Iron-Binding Capacity, Serum. Mayo Clinic Mayo Medical Laboratories [On-line information]. Available online at http://www.mayomedicallaboratories.com/test-catalog/Overview/34624 through http://www.mayomedicallaboratories.com. Accessed April 2013.

Devkota, B. (Updated October 4). Iron-Binding Capacity. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/2085726-overview through http://emedicine.medscape.com. Accessed April 2013.

(Update 2013 March). Hemochromatosis. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/Hemochromatosis.html?client_ID=LTD#tabs=6 through http://www.arupconsult.com. Accessed April 2013.

Yamanishi, H. et. al. (2003 January). Total Iron-binding Capacity Calculated from Serum Transferrin Concentration or Serum Iron Concentration and Unsaturated Iron-binding Capacity. Clinical Chemistry v 49 (1) 175-178 [On-line information]. Available online at http://www.clinchem.org/content/49/1/175.full through http://www.clinchem.org. Accessed April 2013.

S6 Pagana, K. D. & Pagana, T. J. (© 2011). Mosby's Diagnostic and Laboratory Test Reference 10th Edition: Mosby, Inc., Saint Louis, MO. Pp 594-598.

Sources Used in Previous Reviews

Corbett, JV. Laboratory Tests & Diagnostic Procedures with Nursing Diagnoses, 4th ed. Stamford, Conn.: Appleton & Lang, 1996. Pp. 34-35, 41-43.

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Boston University Medical Center. Community Outreach Health Information System. Available online at http://www.bu.edu/cohis/cardvasc/blood/anemia.htm#prevent through http://www.bu.edu.

Lyon, Elaine and Frank, Elizabeth L. Hereditary Hemochromatosis Since Discovery of the HFE Gene. Clinical Chemistry 47:1147-1156 (Jul 2001).

Pagana, K. D. & Pagana, T. J. (© 2007). Mosby's Diagnostic and Laboratory Test Reference 8th Edition: Mosby, Inc., Saint Louis, MO. Pp 574-577.

Clarke, W. and Dufour, D. R., Editors (© 2006). Contemporary Practice in Clinical Chemistry: AACC Press, Washington, DC. Pp 43, 200-201.

Wu, A. (© 2006). Tietz Clinical Guide to Laboratory Tests, 4th Edition: Saunders Elsevier, St. Louis, MO. Pp 1062-1065.

Dugdale III, D. (Updated 2009 February 13). Total Iron Binding Capacity. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/003489.htm. Accessed June 2009.

(Modified 2009 March 13). About Iron. Iron Disorders Institute [On-line information]. Available online at http://www.irondisorders.org/Disorders/about.asp through http://www.irondisorders.org. Accessed June 2009.

(Updated 2007 August 24). Dietary Supplement Fact Sheet: Iron. NIH Office of Dietary Supplements [On-line information]. Available online at http://ods.od.nih.gov/factsheets/iron.asp through http://ods.od.nih.gov. Accessed June 2009.

Rathz, D. et. al. (Updated 2009 February 02). Toxicity, Iron. eMedicine [On-line information]. Available online at http://emedicine.medscape.com/article/166933-overview through http://emedicine.medscape.com. Accessed June 2009.

Chen, Y. (Updated 2009 April 05). Iron Deficiency Anemia. MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000584.htm. Accessed June 2009.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson RA and Pincus MR, eds. Philadelphia: 2007, Pg 506.