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Second Trimester Maternal Serum Screening

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Also known as: AFP Maternal; Maternal Serum AFP; MSAFP; msAFP; Triple Screen; Triple Test; Quad Screen; Quadruple Marker Test; 4-marker Screen; Multiple Marker Test
Formal name: Maternal Serum Screen

Were you looking instead for AFP tumor markers, used to help diagnose and monitor therapy for certain cancers of the liver, testes, or ovaries?

At a Glance

Why Get Tested?

To assess the risk of a fetus having certain chromosomal abnormalities, such as Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18), and open neural tube defects, such as spina bifida

When to Get Tested?

Usually between the 15th and 20th weeks of pregnancy

Sample Required?

A blood sample drawn from a vein in your arm

Test Preparation Needed?

None