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Conn Syndrome

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The goals of treating Conn syndrome are to lower blood pressure to normal or near normal levels, decrease blood aldosterone levels, and resolve any electrolyte imbalances. The type(s) of treatment depends on the cause of the excess aldosterone secretion.

If it is due to a single benign adrenal tumor, then the affected gland may be surgically removed. In many cases, this will completely resolve hypertension and other associated symptoms; however, in other cases, additional treatment will be necessary to fully control blood pressure.

If the primary aldosteronism is due to a cancerous tumor, which is rare, then organs located next to the affected adrenal gland will need to be evaluated during surgery and more than the adrenal gland may need to be removed.

If the cause of the primary aldosteronism cannot be determined (idiopathic) or appears to be due to hyperplasia in both adrenal glands, then surgery is usually not recommended. Treatment with a drug such as spironolactone to block the action of aldosterone and with one or more blood pressure drug therapies may be indicated.

Those affected by Conn syndrome should consult with their doctors and, when indicated, with an endocrinologist (a specialist in the endocrine system). Treatment for primary aldosteronism must often be adjusted to accommodate underlying hypertension, kidney disease, congestive heart failure, and a variety of other disorders. Lifestyle changes, such as dietary changes and exercise, may improve response to hypertension medications.

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