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Disseminated Intravascular Coagulation

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Tests: Prothrombin Time and International Normalized Ratio, PTT, Fibrinogen, Complete Blood Count, D-Dimer, Comprehensive Metabolic Panel
Conditions: Excessive Clotting Disorders, Bleeding Disorders, Sepsis, Pregnancy, Stroke, Leukemia

Elsewhere On The Web
National Heart, Lung, and Blood Institute: What Is Disseminated Intravascular Coagulation?
MedlinePlus Medical Encyclopedia: Disseminated intravascular coagulation (DIC)
American Society of Hematology: Blood Clots

Article Sources

NOTE: This article is based on research that utilizes the sources cited here as well as the collective experience of the Lab Tests Online Editorial Review Board. This article is periodically reviewed by the Editorial Board and may be updated as a result of the review. Any new sources cited will be added to the list and distinguished from the original sources used. To access online sources, copy and paste the URL into your browser.

Sources Used in Current Review

(Oct 9, 2015) Levi, M. Disseminated Intravascular Coagulation. Medscape Reference. Available online at http://emedicine.medscape.com/article/199627-overview. Accessed March 2016.

Wintrobe's Clinical Hematology. 12th ed. Greer J, Foerster J, Rodgers G, Paraskevas F, Glader B, Arber D, Means R, eds. Philadelphia, PA: Lippincott Williams & Wilkins: 2009, Pp 1430-1431, 1436-1437.

(Oct 13, 2015) Gozman, A. Consumption Coagulopathy. Medscape Reference. Available online at http://emedicine.medscape.com/article/955059-overview. Accessed March 2016.

Okamoto K, et al. Sepsis and disseminated intravascular coagulation. J Intensive Care. 2016; 4: 23. Published online 2016 Mar 23. Available online at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804491/. Accessed March 2016.

Sources Used in Previous Reviews

Becker, J. et. al. (Updated 2011 August 9). Disseminated Intravascular Coagulation in Emergency Medicine. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/779097-overview. Accessed October 2011.

Dugdale, D. (Updated 2010 December 28). Disseminated intravascular coagulation (DIC). MedlinePlus Medical Encyclopedia [On-line information]. Available online at http://www.nlm.nih.gov/medlineplus/ency/article/000573.htm. Accessed October 2011.

Kanwar, V. and Sills, R. (Updated 2011 August 10). Consumption Coagulopathy. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/955059-overview. Accessed October 2011.

(Updated 2010 February 1). Disseminated Intravascular Coagulation. National Heart Lung and Blood Institute [On-line information]. Available online at http://www.nhlbi.nih.gov/health/health-topics/topics/dic/. Accessed October 2011.

Levi, M. and Schmaier, A. (Updated 2011 August 2). Disseminated Intravascular Coagulation. Medscape Reference [On-line information]. Available online at http://emedicine.medscape.com/article/199627-overview. Accessed October 2011.

Lehman, C. (Updated 2011 January). Disseminated Intravascular Coagulation – DIC. ARUP Consult [On-line information]. Available online at http://www.arupconsult.com/Topics/DIC.html. Accessed October 2011.

Moake, J. (Updated 2009 June). Disseminated Intravascular Coagulation (DIC). Merck Manual for Healthcare Professionals [On-line information]. Available online through http://www.merckmanuals.com. Accessed October 2011.

Moake, J. (Updated 2009 June). Overview of Hemostasis. Merck Manual for Healthcare Professionals [On-line information]. Available online at http://www.merckmanuals.com/professional/hematology_and_oncology/hemostasis/overview_of_hemostasis.html#v971842. Accessed October 2011.

Semeraro, N. et. al. (2010 August 13). Sepsis-Associated Disseminated Intravascular Coagulation and Thromboembolic Disease. Medit J Hemat Infect Dis 2010, 2(3): e2010024 [On-line information]. PDF available for download at http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3033145/pdf/mjhid-2-3-e2010024.pdf. Accessed October 2011.

Harmening, D. Clinical Hematology and Fundamentals of Hemostasis, Fifth Edition, F.A. Davis Company, Philadelphia, 2009, Pp 648-655.

Henry's Clinical Diagnosis and Management by Laboratory Methods. 21st ed. McPherson R, Pincus M, eds. Philadelphia, PA: Saunders Elsevier: 2007, Pg 742.

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